Figure 5. Possible kinds of changes in cell lineage pattern (redrawn from Sommer et al.

Figure 5

Possible kinds of changes in cell lineage pattern (redrawn from Sommer et al. 1994). (P) Precursor cell; (A–D) different cell types. Because these changes are similar to known mutations, possible loci contributing to such changes have been suggested (Sommer et al. 1994), corresponding to the numbered boxes as follows. (1) Mutations in ces-1 and ces-2 cause programmed death of specific cells (if D represents a cell death, for example); (2) mutations in lin-18 and lin-44 cause altered polarity of cell lineages; (3) mutations in unc-86 result in reiterations of some lineages; (5) mex-1 mutations cause defective localization of the SKN-1 determinant. Sommer et al. (1994) also cite specific examples of interspecific lineage differences; for example, (4) Z1 division is delayed in P. redivivus relative to C. elegans.

From: Section III, Character Evolution

Cover of C. elegans II
C. elegans II. 2nd edition.
Riddle DL, Blumenthal T, Meyer BJ, et al., editors.
Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 1997.
Copyright © 1997, Cold Spring Harbor Laboratory Press.

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