Chemosensation and thermosensation are two important sensory mechanisms that Caenorhabditis elegans uses to interact with its environment. Behavioral and genetic similarities between chemotaxis and thermotaxis indicate that these two types of tracking behaviors share molecular and cellular components.
C. elegans modifies many aspects of its behavior on the basis of chemical cues. Bacteria (its food) or bacterial metabolites stimulate feeding, defecation, and egg laying (Horvitz et al. 1982; Avery and Horvitz 1990; Thomas 1990; Avery and Thomas, this volume). The chemosensory system also detects a pheromone that regulates entry into the alternative dauer larva stage (see Riddle, this volume). Other pheromones contribute to mating between males and hermaphrodites (see Emmons and Sternberg, this volume). This chapter focuses on chemotaxis, the migration of animals toward bacteria (their food) or defined chemicals (Ward 1973; Dusenbery 1974).
Temperature is a major determinant of the animal's metabolism. As a cold-blooded animal, C. elegans has a limited temperature range (∼12− 26°C) at which it is viable and fertile. Thermotaxis behaviors allow animals to track to a preferred temperature (see Hedgecock and Russell 1975).
Cold Spring Harbor Laboratory Press, Cold Spring Harbor (NY)
Riddle DL, Blumenthal T, Meyer BJ, et al., editors. C. elegans II. 2nd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 1997. Section I, Introduction.