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Cover of Itch


Mechanisms and Treatment

Frontiers in Neuroscience

Editors: E Carstens and Tasuku Akiyama.

Editor Information
Boca Raton (FL): CRC Press/Taylor & Francis; .
ISBN-13: 978-1-4665-0543-8

Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There has been a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain.

Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphoma, and systemic diseases such as kidney and liver disease and cancer.

Composed of contributions from distinguished researchers around the world, the book explores topics such as

  • Neuropathic itch
  • Peripheral neuronal mechanism of itch
  • The role of PAR-2 in neuroimmune communication and itch
  • Mrgprs as itch receptors
  • The role of interleukin-31 and oncostatin M in itch and neuroimmune communication
  • Spinal coding of itch and pain
  • Spinal microcircuits and the regulation of itch

Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.


© 2014 by Taylor & Francis Group, LLC.
Bookshelf ID: NBK200931PMID: 24830003


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