FIGURE 20.7. Assembly of Kdo2–lipid A in E.

FIGURE 20.7

Assembly of Kdo2–lipid A in E. coli. LpxA, LpxC, and LpxD are cytoplasmic enzymes, whereas LpxH and LpxB are peripheral membrane proteins. The remaining enzymes are integral inner-membrane proteins, with their active sites facing the cytoplasm. The numbers below the fatty acid chains indicate the predominant fatty acid chain lengths found in E. coli lipid A. (Adapted, with permission, from Raetz C.R.H., Reynolds C.M., Trent M.S., et al. 2007. Annu. Rev. Biochem. 76: 295–329, ©Annual Reviews.)

Download Teaching Slide (PPT, 482K)

From: Chapter 20, Eubacteria and Archaea

Cover of Essentials of Glycobiology
Essentials of Glycobiology. 2nd edition.
Varki A, Cummings RD, Esko JD, et al., editors.
Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2009.
Copyright © 2009, The Consortium of Glycobiology Editors, La Jolla, California.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.