FIGURE 41.1. Degradation of complex N-glycans.

FIGURE 41.1

Degradation of complex N-glycans. The lysosomal degradation pathway of glycoproteins carrying complex-type glycans proceeds simultaneously on both the protein and glycan moieties. The N-glycans are sequentially degraded by the indicated exoglycosidases in a specific order as discussed in the text.

Symbol Key: FIGURE 41.1. Degradation of complex N-glycans.

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From: Chapter 41, Genetic Disorders of Glycan Degradation

Cover of Essentials of Glycobiology
Essentials of Glycobiology. 2nd edition.
Varki A, Cummings RD, Esko JD, et al., editors.
Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2009.
Copyright © 2009, The Consortium of Glycobiology Editors, La Jolla, California.

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