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Excerpt
This small book owes its existence in large part to Jean Strouse. Late in 2003, when she was still the freshly appointed director of The New York Public Library’s Cullman Center for Scholars and Writers, Jean asked me to give a series of three lectures the following fall, an annual event sponsored by W. W. Norton & Company, hoping that I would speak about some aspects of the relationship between the sciences and the humanities. This notion was inspired, in part, by her long-range goal of using her new position to promote a greater interest in and knowledge about science among her colleagues in the humanities. I was asked because she knew that I had studied literature in earlier years and continue to read widely in realms beyond the science that I practice.
At first, she suggested that I revisit the concept of two cultures, which is generally traced to the 1959 Rede Lecture delivered by C. P. Snow, who had achieved prominence as a scientist, a novelist, and a government official. Snow’s description of the two cultures, the arts and the sciences, separated by a gulf of language and thought, met with both hearty acclaim and strident criticism, and the subsequent debates attracted enormous attention. (I recall an evening given over to an American version of the debate at a fraternity house at Amherst College in 1960, when I was an undergraduate there.)
But on rereading both the original lecture and Snow’s responses to his critics, I found (and Jean did too) that the idea of two cultures now appeared too simplistic, however accurate, to bear a lengthy reexamination. So, after a series of lunches and email exchanges, we agreed that I would endeavor to explain what it means to be a scientist—or, anyhow, what it has meant for me to be a scientist. That seemed to be a way to fulfill at least part of her original purpose, since I came to science through an education in the humanities, and my career as a scientist has included significant forays into politics, administration, publishing, and international issues. By defining my purpose in this manner, I hoped to make some aspects of the life and thoughts of one scientist intelligible and possibly interesting to even the most entrenched members of the “other” culture.
To do this, I intended to use my three lectures to describe three things: first, how I became a scientist; then, something about the work my colleagues and I have done and its significance for the control of cancer; and, finally, examples of my experience in government and policy-making, to offer a view of a scientist in a larger world that includes politics and the arts. The assignment encouraged me to think more than I would otherwise have done about the shape of my career, which revealed to me how meandering and unexpected it has been. This theme—with implicit course changes and serendipities—became a dominant one in the lectures and even more so in this volume.
Contents
- Dedication
- Preface
- Introduction
- PART ONE. BECOMING A SCIENTIST
- PART TWO. DOING SCIENCE
- PART THREE. A POLITICAL SCIENTIST
- PART FOUR. CONTINUING CONTROVERSIES
- 13. Embryos, Cloning, Stem Cells, and the Promise of Reprogramming
- Thinking about Research with Human Embryos
- Political Consequences of the Human Embryo Research Panel Report
- The Birth of Dolly and the Specter of Human Reproductive Cloning
- Dolly’s Significance: Genetic Reprogramming
- Avoiding Legislation to Criminalize Nuclear Transfer
- Growing Human Embryonic Stem Cells
- Stem Cells in the Era of George W. Bush
- 14. Global Science and Global Health
- 15. Science Publishing and Science Libraries in the Internet Age
- Becoming an Advocate for New Practices
- How Scientists Are Affected by Publication Practices
- PubMed: Virtues and Limitations
- Why Scientists Love Certain Journals
- A Brief History of Science Publishing
- The Business of Science Publishing
- My Conversion: The Making of a Radical
- Taking On the Problem: E-biomed
- How E-biomed Became a Public Library: The Birth of PubMed Central
- The Origins of PLoS: From Advocacy to Open Access Publishing
- PLoS Becomes a Publisher of Open Access Journals
- Support for Public Access from Those Who Fund Research
- A Final Word about Publication Practices
- 13. Embryos, Cloning, Stem Cells, and the Promise of Reprogramming
- Epilogue: A Life in Science
- Glossary
- References
- Acknowledgments
- Photographs
- NLM CatalogRelated NLM Catalog Entries
- Rules to be adopted for publishing a scientific paper.[Ann Ital Chir. 2016]Rules to be adopted for publishing a scientific paper.Picardi N. Ann Ital Chir. 2016; 87:1-3.
- EMPIRICISM IN LATTER-DAY BEHAVIORAL SCIENCE.[Science. 1964]EMPIRICISM IN LATTER-DAY BEHAVIORAL SCIENCE.BIXENSTINE VE. Science. 1964 Jul 31; 145(3631):464-7.
- Pilot Medical Certification.[StatPearls. 2026]Pilot Medical Certification.Matthews MJ, Stretanski MF. StatPearls. 2026 Jan
- Review Challenges and Role Changes in Caring for Adult Children With Cancer.[J Adv Pract Oncol. 2018]Review Challenges and Role Changes in Caring for Adult Children With Cancer.Bourdeanu L, Cannistraci P. J Adv Pract Oncol. 2018 Sep-Oct; 9(6):634-638. Epub 2018 Sep 1.
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- The Art and Politics of ScienceThe Art and Politics of Science
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