Table 9

Cumulative cancer risk by site and age (population risk) from a study of 416 Peutz-Jeghers syndrome patients

Type of cancerCumulative cancer risk by site and age (population risk) from a study of 416 Peutz-Jeghers syndrome patients
20 yrs30 yrs40 yrs50 yrs60 yrs70 yrs
All cancers2 (0.3)5 (0.6)17 (1.4)31 (3.4)60 (8.2)85 (17.7)
Gastrointestinal
  • (<0.1)
1 (<0.1)9 (0.1)15 (0.3)33 (1.3)57 (3.9)
Breast
  • (<0.1)
  • (<0.1)
8 (0.5)13 (1.8)31 (4.3)45 (7.0)
Gynecological
  • (<0.1)
1 (0.1)3 (0.4)8 (0.7)18 (1.3)18 (2.1)
Pancreas
  • (<0.1)
  • (<0.1)
3 (<0.1)5 (<0.1)7 (0.2)11 (0.5)
Lung (males)
  • (<0.1)
  • (<0.1)
1 (0.1)4 (0.2)13 (1.3)17 (4.7)

Reproduced with permission from Hearle and others with permission from the American Association for Cancer Research.(28)

From: Peutz-Jeghers Syndrome

Cover of Cancer Syndromes
Cancer Syndromes [Internet].
Riegert-Johnson DL, Boardman LA, Hefferon T, et al., editors.
Copyright © 2009-, Douglas L Riegert-Johnson.

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