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McIntosh B, Clark M, Spry C. Benzodiazepines in Older Adults: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2011 Jan.

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Benzodiazepines in Older Adults: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines [Internet].

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REFERENCES

1.
Mohler H, Fritschy JM, Rudolph U. A new benzodiazepine pharmacology. J Pharmacol Exp Ther. 2002 Jan;300(1):2–8. [PubMed: 11752090]
2.
e-CPS [Internet] Benzodiazepines. Ottawa: Canadian Pharmacists Association; 2009. [cited 2010 Sep 15]. Available from: https://www​.e-therapeutics.ca Subscription required.
3.
Petrovic M, Mariman A, Warie H, Afschrift M, Pevernagie D. Is there a rationale for prescription of benzodiazepines in the elderly? Review of the literature. Acta Clin Belg. 2003 Jan;58(1):27–36. [PubMed: 12723259]
4.
Grad RM. Benzodiazepines for insomnia in community-dwelling elderly: a review of benefit and risk. J Fam Pract. 1995 Nov;41(5):473–481. [PubMed: 7595266]
5.
Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med. 2003 Dec 8;163(22):2716–2724. [PubMed: 14662625]
6.
Mamdani M, Rapoport M, Shulman KI, Herrmann N, Rochon PA. Mental health-related drug utilization among older adults: prevalence, trends, and costs. Am J Geriatr Psychiatry. 2005 Oct;13(10):892–900. [PubMed: 16223968]
7.
Woolcott JC, Richardson KJ, Wiens MO, Patel B, Marin J, Khan KM, et al. Meta-analysis of the impact of 9 medication classes on falls in elderly persons. Arch Intern Med. 2009 Nov 23;169(21):1952–1960. [PubMed: 19933955]
8.
Hartikainen S, Lönnroos E, Louhivuori K. Medication as a risk factor for falls: critical systematic review. J Gerontol A Biol Sci Med Sci. 2007 Oct;62(10):1172–1181. [PubMed: 17921433]
9.
Verdoux H, Lagnaoui R, Begaud B. Is benzodiazepine use a risk factor for cognitive decline and dementia? A literature review of epidemiological studies. Psychol Med. 2005 Mar;35(3):307–315. [PubMed: 15841867]
10.
Takkouche B, Montes-Martinez A, Gill SS, Etminan M. Psychotropic medications and the risk of fracture: a meta-analysis. Drug Saf. 2007;30(2):171–184. [PubMed: 17253881]
11.
Glass J, Lanctt KL, Herrmann N, Sproule BA, Busto UE. Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits. J Law Med. 2005;331(7526):1169–1173. [PMC free article: PMC1285093] [PubMed: 16284208]
12.
Charlson F, Degenhardt L, McLaren J, Hall W, Lynskey M. A systematic review of research examining benzodiazepine-related mortality. Pharmacoepidemiol Drug Saf. 2009 Feb;18(2):93–103. [PubMed: 19125401]
13.
Clinical practice guidelines and protocols in British Columbia. Victoria (BC): Province of British Columbia Ministry of Health Services; 2007. [cited2010 Nov 17]. Cognitive Impairment in the elderly - recognition, diagnosis and management [Internet] Available from: http://www​.bcguidelines​.ca/gpac/pdf/cognitive.pdf.
14.
National Collaborating Centre for Mental Health. Dementia: the NICE-SCIE guideline on supporting people with dementia and their carers in health and social care [Internet]. London: British Psychological Society, Royal College of Psychiatrists; 2007. [cited 2010 Nov 16]. (National clinical practice guideline number 42). Available from: http://www​.nice.org.uk​/nicemedia/live/10998/30320/30320.pdf. [PubMed: 21834193]
15.
Management of patients with dementia: a national clinical guideline [Internet]. Edinburgh: Scottish Intercollegiate Guidelines Network (SIGN); 2006. [cited 2010 Nov 16]. (Guideline no. 86). Available from: http://www​.sign.ac.uk/pdf/sign86.pdf.
16.
Rabins PV, Blacker D, Rovner BW, Rummans T, Schneider LS, Tariot PN, et al. American Psychiatric Association practice guideline for the treatment of patients with Alzheimer's disease and other dementias. Second edition. Am J Psychiatry [Internet] 2007 Dec;164(12 Suppl):5–56. [cited 2010 Nov 17]; Available from: http://www​.psychiatryonline​.com/pracGuide​/PracticePDFs/AlzPG101007.pdf. [PubMed: 18340692]
17.
Conn DK, Gibson M, Feldman S, Hirst S, Leung S, MacCourt P, et al. National guidelines for seniors' mental health: the assessment and treatment of mental health issues in long-term care homes (focus on mood and behaviour symptoms) Can J Geriatr [Internet] 2010 9 Suppl 2:59–64. [cited 2010 Nov 17]; Available from: http://www​.ccsmh.ca/pdf​/final%20supplement.pdf.
18.
Stein MB, Goin MK, Pollack MH, Roy-Byrne P, Sareen J, Simon NM, et al. Practice guideline for the treatment of patients with panic disorder [Internet]. Second ed. Washington (DC): American Psychiatric Association (APA); 2009. [cited 2010 Aug 30]. Available from: http://www​.psychiatryonline​.com/pracGuide​/PracticePDFs/PanicDisorder​_2e_PracticeGuideline.pdf.
19.
National Guideline Clearinghouse [Internet] c2009 -. Sleep disorders. Rockville (MD): National Guideline Clearinghouse; 2006. [cited 2010 Aug 30]. Available from: http://www​.guideline​.gov/content.aspx?id=9381.
20.
NIH State-of-the-Science Conference Statement on manifestations and management of chronic insomnia in adults. NIH Consens State Sci Statements. 2005 Jun 13;22(2):1–30. [PubMed: 17308547]
21.
Montgomery P, Lilly J. Insomnia in the elderly. Clin Evid [Internet]. 2007 [cited 2010 Aug 31]; Available from: http://www​.ncbi.nlm.nih​.gov/pmc/articles​/PMC2943793/?tool=pubmed. [PMC free article: PMC2943793] [PubMed: 19450355]
22.
Leipzig RM, Cumming RG, Tinetti ME. Drugs and falls in older people: a systematic review and meta-analysis: I. Psychotropic drugs. J Am Geriatr Soc. 1999 Jan;47(1):30–39. [PubMed: 9920227]
23.
Leipzig RM, Cumming RG, Tinetti ME. Drugs and falls in older people: a systematic review and meta-analysis: II. Cardiac and analgesic drugs. J Am Geriatr Soc. 1999 Jan;47(1):40–50. [PubMed: 9920228]
24.
Downs SH, Black N. The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. J Epidemiol Community Health [Internet]. 1998 Jun;52(6):377–384. [cited 2010 Sep 15]; Available from: http://www​.ncbi.nlm.nih​.gov/pmc/articles/PMC1756728. [PMC free article: PMC1756728] [PubMed: 9764259]
25.
Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. J Law Med [Internet]. 1997 Sep 13;315(7109):629–634. [cited 2010 Sep 30]; Available from: http://www​.ncbi.nlm.nih​.gov/pmc/articles​/PMC2127453/pdf/9310563.pdf. [PMC free article: PMC2127453] [PubMed: 9310563]
26.
Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials. 1996 Feb;17(1):1–12. [PubMed: 8721797]
27.
Shea B. A MeaSurement Tool to Assess Reviews (AMSTAR). Ottawa: Institute of Population Health; Oct, 2005.
28.
Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. J Law Med [Internet]. 2008 Apr 26;336(7650):924–926. [cited 2010 Oct 1]; Available from: http://www​.bmj.com/ Subscription required. [PMC free article: PMC2335261] [PubMed: 18436948]
29.
The AGREE Collaboration. London: St. George's Hospital Medical School; Appraisal of guidelines for research & evaluation (AGREE) instrument [Internet] 2001 Sep [cited 2010 Sep 30]; Available from: http://www​.agreecollaboration​.org/pdf/agreeinstrumentfinal​.pdf.
30.
Clinical evidence [Internet]. London: BMJ Publishing Group; 2010. [cited 2010 Sep 27]. About us: a guide to the text; 2009. Available from: http:​//clinicalevidence​.bmj.com/ceweb/about/guide.jsp.
31.
Definition of an older or elderly person [Internet]. Geneva: World Health Organization (WHO); 2001. [cited 2010 Oct 1]. Available from: http://www​.who.int/healthinfo​/survey/ageingdefnolder​/en/print.html.
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Bookshelf ID: NBK174571

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