Table 2Plasma Stability and Plasma Protein Binding of ML338 and CID 2843335

Image ml338fu1.jpg
Image ml338fu2.jpg
PubChem CID Probe/Hit60182306 Probe, ML3382843335 HTS Hit
Plasma stability (% remaining after 5 hours)Human100%89.6%
Murine92.3%71.3%
Plasma protein binding (% bound)Human96.399.7
Murine98.899.3

From: Elucidation of the physiology of non-replicating, drug tolerant Mycobacterium tuberculosis with the aid of the small molecule probe ML338

Cover of Probe Reports from the NIH Molecular Libraries Program
Probe Reports from the NIH Molecular Libraries Program [Internet].

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.