Scheme 1. The synthetic route to ML321 is a multi-step process with 8 compound intermediates (A – H).

Scheme 1The synthetic route to ML321 is a multi-step process with 8 compound intermediates (A – H)

From: Discovery, optimization, and characterization of a novel series of dopamine D2 versus D3 receptor selective antagonists

Cover of Probe Reports from the NIH Molecular Libraries Program
Probe Reports from the NIH Molecular Libraries Program [Internet].

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.