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Diagnostic Criteria and Classification of Hyperglycaemia First Detected in Pregnancy. Geneva: World Health Organization; 2013.

Cover of Diagnostic Criteria and Classification of Hyperglycaemia First Detected in Pregnancy

Diagnostic Criteria and Classification of Hyperglycaemia First Detected in Pregnancy.

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Annex 2Summary Tables

Table 1. Sensitivity analysis of the impact of screening strategies on the incidence of large for gestational age (LGA) birth and pre-eclampsia, considering different prevalences (WHO criteria) of gestational diabetes (GDM) and assuming different increases in the prevalence with the use of the IADPSG criteria instead of those of WHO (PDF, 202K)

Results of the baseline case (WHO prevalence 10%; increase in prevalence with use of the IADPSG criteria of 50%) are shown in bold.

Table 2. Prognostic properties of 1999 WHO diagnostic criteria for gestational diabetes mellitus (GDM) in predicting large for gestational age (LGA) births (PDF, 278K)

Population / Setting: pregnant women from the general population submitted to universal screening for GDM at 24-28 weeks

Test : 75g-OGTT applying the 1999 WHO cut-offs

Clinical outcome: LGA births

Table 3. Prognostic properties of the IADPSG diagnostic criteria for gestational diabetes mellitus (GDM) in predicting large for gestational age (LGA) births (PDF, 289K)

Population / Setting: pregnant women from the general population submitted to universal screening for GDM at 24-28 weeks

Test : 75g-OGTT applying the IADPSG cut-offs

Clinical outcome: LGA births

Table 4. Prognostic properties of 1999 WHO diagnostic criteria for gestational diabetes mellitus (GDM) in predicting pre-eclampsia (PDF, 278K)

Population / Setting: pregnant women from the general population submitted to universal screening for GDM at 24-28 weeks

Test : 75g-OGTT applying the 1999 WHO cut-offs

Clinical outcome: development of pre-eclampsia during pregnancy

Table 5. Prognostic properties of the IADPSG diagnostic criteria for gestational diabetes mellitus (GDM) in predicting pre-eclampsia (PDF, 289K)

Population / Setting: pregnant women from the general population submitted to universal screening for GDM at 24-28 weeks

Test : 75g-OGTT applying the IADPSG cut-offs

Clinical outcome: development of pre-eclampsia during pregnancy

Table 6. Prognostic properties of 1999 WHO diagnostic criteria for gestational diabetes mellitus (GDM) in predicting caesarean section (PDF, 289K)

Population / Setting: pregnant women from the general population submitted to universal screening for GDM at 24-28 weeks

Test : 75g-OGTT applying the 1999 WHO cut-offs

Clinical outcome: caesarean section

Table 7. Prognostic properties of the IADPSG diagnostic criteria for gestational diabetes mellitus (GDM) in predicting caesarean section (PDF, 289K)

Population / Setting: pregnant women from the general population submitted to universal screening for GDM at 24-28 weeks

Test : 75g-OGTT applying the IADPSG cut-offs

Clinical outcome: caesaraean section

Table 8. GRADE Evaluation of specific treatment for gestational diabetes based on adverse perinatal outcomes (PDF, 284K)

Specific treatment for GDM compared to usual care for preventing adverse perinatal outcomes in women with GDM

Population: women with GDM

Intervention: any kind of specific GDM treatment

Comparison: usual antenatal care

Outcome: adverse perinatal outcomes

Table 9. GRADE Evaluation of specific treatment for gestational diabetes based on adverse maternal outcomes (PDF, 269K)

Specific treatment for GDM compared to usual care for preventing adverse maternal outcomes in women with GDM

Population: women with GDM

Intervention: any kind of specific GDM treatment

Comparison: usual antenatal care

Outcome: adverse maternal outcomes

Table 10. GRADE Evaluation of GDM screening based on the universal application of the WHO criteria (PDF, 262K)

Universal screening for GDM according to WHO criteria compared to no screening in pregnancy

Population: pregnant women from the general population

Intervention: OGGT, with specific treatment for women diagnosed with GDM according to WHO criteria

Comparison: no screening

Outcome: adverse perinatal and maternal outcomes

Table 11. GRADE Evaluation of GDM screening based on the universal application of the IADPSG criteria (PDF, 262K)

Universal screening for GDM according to IADPSG criteria compared to no screening in pregnancy

Population: pregnant women from the general population

Intervention: OGGT, with specific treatment for women diagnosed with GDM according to IADPSG criteria

Comparison: no screening

Outcome: adverse perinatal and maternal outcomes

Table 12. GRADE Evaluation of GDM screening comparing the universal application of the IADPSG and the WHO criteria (PDF, 262K)

Universal creening for GDM according to IADPSG criteria compared to screening according to WHO criteria

Population: pregnant women from general population

Intervention: OGGT, with specific treatment for women diagnosed with GDM according to IADPSG criteria

Comparison: OGGT, with specific treatment for women diagnosed with GDM according to WHO criteria

Outcome: adverse perinatal and maternal outcomes

Copyright © World Health Organization 2013.

All rights reserved. Publications of the World Health Organization can be obtained from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: tni.ohw@sredrokoob). Requests for permission to reproduce or translate WHO publications – whether for sale or for noncommercial distribution – should be addressed to WHO Press, at the above address (fax: +41 22 791 4806; e-mail: tni.ohw@snoissimrep).

Bookshelf ID: NBK169021

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