Cover of The Genetic Landscape of Diabetes

The Genetic Landscape of Diabetes

, MD and , PhD.

National Center for Biotechnology Information (US), National Library of Medicine, National Institutes of Health, Bethesda, MD 20892-6510

"The Genetic Landscape of Diabetes" introduces the reader to what diabetes is—from its discovery thousands of years ago to our modern-day understanding of how this disease, characterized by high blood sugar, develops.

The first chapter provides calculators that help you calculate your ideal body weight and BMI. Animated maps of the United States show the rise in obesity and diabetes.

Other chapters guide the reader through the genetic variations that may play roles in type 1 diabetes, type 2 diabetes, and other types. The genes discussed encode proteins that have diverse functions in cells—from transcription factors that influence the expression of other genes, to ion channels that control the release of insulin, from transporters that pump glucose into cells, to enzymes that speed up the break down of glucose.

The book closes with "NIH lectures"—videos of some of the most recent lectures given by researchers who have been invited to the NIH to discuss obesity and diabetes.