Figure 11.2. Age-specific incidence of inherited familial adenomatous polyposis (FAP) and sporadic colon cancer.

Figure 11.2

Age-specific incidence of inherited familial adenomatous polyposis (FAP) and sporadic colon cancer. (a) Inherited colon cancer (FAP) caused by mutation of the APC gene (top curve) and sporadic cases (bottom curve) per 106 population, shown on a log10 scale. (b) Ratio, R, of sporadic colon cancer incidence to inherited FAP incidence at each age multiplied by 10−4, using the data in the previous panel. (c) The difference in the log-log acceleration between sporadic and inherited cases, which is the log-log slope of R. I presented this figure earlier as Figure 8.5; see my earlier presentation for more details.

From: Chapter 11, Inheritance

Cover of Dynamics of Cancer
Dynamics of Cancer: Incidence, Inheritance, and Evolution.
Frank SA.
Princeton (NJ): Princeton University Press; 2007.
Copyright © 2007, Steven A Frank.

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