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Stein E, Clarke JO, Hutfless S, et al. Wireless Motility Capsule Versus Other Diagnostic Technologies for Evaluating Gastroparesis and Constipation: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 110 [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2013 May. (Future Research Needs Papers, No. 27.)

Cover of Wireless Motility Capsule Versus Other Diagnostic Technologies for Evaluating Gastroparesis and Constipation: Future Research Needs

Wireless Motility Capsule Versus Other Diagnostic Technologies for Evaluating Gastroparesis and Constipation: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 110 [Internet].

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Appendix CIndividual Stakeholder Priority Scores for Future Research Questions

TopicStakeholder 1Stakeholder 2Stakeholder 3Stakeholder 4Stakeholder 5Stakeholder 6Stakeholder 7Stakeholder 8Stakeholder 9Sum
(highest sum = highest priority)
Priority Rank
(1 = highest priority)
List 1: Clinical Research
The individual stakeholder ratings have been inverted so that the highest value (6) is the highest priority.
Top Tier
1. Comparative effectiveness of managing with WMC (gastric dysmotility/gastroparesis)64646261
2. Comparative diagnostic accuracy and safety (gastric dysmotility/gastroparesis)46445232
3. Gold standard (gastric dysmotility/gastroparesis)1666193
4. Comparison of WMC and scintigraphy results (gastroparesis)6435184
5. Gold standard (colonic dysmotility/slow-transit constipation)554145
6. Reproducibility of WMC results (gastroparesis)5243145
7. Comparative diagnostic accuracy and safety (colonic dysmotility/slow-transit constipation)551116
8. Incremental diagnostic accuracy (gastric dysmotility/gastroparesis)325107
9. Incremental diagnostic accuracy (colonic dysmotility/slow-transit constipation)21698
Other Gaps
10. Distinction of subtypes of gastroparesis (gastric dysmotility/gastroparesis)12479
11. Best test or combination for predicting outcomes after colectomy (colonic dysmotility/slow-transit constipation)5279
12. Comparative accuracy in predicting response to treatment (colonic dysmotility/slow-transit constipation)33179
13. Utility of colonic pressure (colonic dysmotility)1121510
14. Differentiating IBS-C from idiopathic constipation (colonic dysmotility/slow-transit constipation)23510
15. Comparisons of WMC pressure profiles (gastroparesis)23510
16. Best test or combination for predicting outcomes without colectomy (colonic dysmotility/slow-transit constipation)31411
17. Comparative accuracy in predicting response to treatment (gastric dysmotility/gastroparesis)2212
18. Comparative value in monitoring response to treatment (gastric dysmotility/gastroparesis)013
19. Comparative value in monitoring response to treatment (colonic dysmotility/slow-transit constipation)013
20. Colonic pressure patterns after waking (colonic dysmotility)013
21. Evaluation of high-amplitude contractions (colonic dysmotility)013
List 2: Questions Involving Methodological Research
Top Tier
1. WMC data in patients with gastric and colonic dysmotility*365767661471
2. WMC data in non-diseased populations*27474772402
3. Rates of test failures and need for additional tests*6655435343
4. WMC diagnostic accuracy and safety in gastroparesis subtypes*7434515294
5. Thresholds*573651275
6. Correlation between WMC values and histopathology*6147186
Other Gaps
7. Colonic pressure patterns following meal ingestion.52413157
8. Relation of baseline WMC values with long-term followup values1336138
9. WMC data compared with other tests in non-diseased populations4323129
10. Concurrent tests1224910
11. Masking interpreters of WMC data122511
12. Use of historical controls in WMC research2212

C = clinical knowledge gap; M = methodological knowledge gap; WMC = wireless motility capsule.

Bookshelf ID: NBK154642

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