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Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet]. York (UK): Centre for Reviews and Dissemination (UK); 1995-.

Cover of Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].

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[Effects of organic selenium supplement on glutathione peroxidase activities: a meta-analysis of randomized controlled trials]

Review published: .

Bibliographic details: Jiang X, Dong J, Wang B, Yin X, Qin L.  [Effects of organic selenium supplement on glutathione peroxidase activities: a meta-analysis of randomized controlled trials]. Journal of Hygiene Research 2012; 41(1): 120-123. [PubMed: 22443071]

Abstract

OBJECTIVE: To study the effects of organic selenium supplementation on glutathione peroxidase (GPx) activities.

METHODS: Randomized controlled trials (RCT) published from January 1988 to December 2010 on the relationship between organic selenium supplementation and GPx activities were collected. Meta-analysis was applied to estimate the combined standardized mean difference (SMD) and 95% confidence interval (95% CI).

RESULTS: A total of 10 RCTs were included. The number of studies observing GPx activities in plasma, erythrocyte and platelet was 8, 5 and 5, respectively. Compared with the controls, the combined SMD (95% CI) of GPx activities in plasma, erythrocyte and platelet of subjects supplemented with organic selenium was 0.46 (0.09 - 0.83), 0.36 (0.02 - 0.69) and 0.56 (-0.02 - 1.15).

CONCLUSION: Supplementation with organic selenium increases GPx activities in healthy adults.

Copyright © 2014 University of York.
Bookshelf ID: NBK153878

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