Table 5Monotherapy and combination treatment comparisons reviewed for pregnant women: Key Question 3

nS-AH, OralaS-AH, OralbINCScD, NasalC, NasaldLRA, OraleAC, NasalfNS
nS-AH, orala
S-AH, oralb
D, nasal
C, nasald
LRA orale
AC, nasalf
nS-AH, orala + NS
S-AH, oralb + NS

The top portion of this table is a grid of monotherapy treatment comparisons included in this review (✓). The last three rows of the table indicate combination treatment comparisons included in this review (✓).

AC = anticholinergic; nS-AH = nonselective antihistamine; S-AH = selective antihistamine; C = cromolyn; INCS = intranasal corticosteroid; LRA = leukotriene receptor antagonist; NS = nasal saline; D = sympathomimetic decongestant.


Chlorpheniramine, clemastine, cyproheptadine, dexchlorpheniramine, and diphenhydramine are Pregnancy Category B.


Cetirizine, loratadine, and levocetirizine are Pregnancy Category B.


Budesonide is Pregnancy Category B.


Cromolyn is Pregnancy Category B.


Montelukast is Pregnancy Category B.


Ipratropium is Pregnancy Category B.

From: Methods

Cover of Treatments for Seasonal Allergic Rhinitis
Treatments for Seasonal Allergic Rhinitis [Internet].
Comparative Effectiveness Reviews, No. 120.
Glacy J, Putnam K, Godfrey S, et al.

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