Appendix Table C66Patient characteristics: combination oral selective antihistamine plus oral decongestant versus oral selective antihistamine

Author, YearDrug, Dose/DayNMean Age, yearsSex, % femaleRace, %Disease Duration, yearsMean Baseline NSSa
Bronsky, 1995Loratadine 10 mg/Pseudoephedrine 240 mg221Median: 30
Range: 12-82
53.8White: 87.3
Black: 5.7
Other: 7.1
Median: 15
Range: 2-47
Loratadine 10 mg217Median: 30
Range: 12-60
57.5White: 87.3
Black: 4.2
Other: 8.5
Median: 15
Range: 1-50
Chervinsky, 2005Desloratadine 5 mg/Pseudoephedrine 240 mg2143664Unspecified18C: 2.55
Desloratadine 5 mg2143769Unspecified19C: 2.56
Grosclaude, 1997Cetirizine 10 mg/Pseudoephedrine 240 mg22731
Range: 9-65
47Unspecified9C: 2.29
R: 1.99
S: 1.93
I: 1.71
Cetirizine 10 mg23132
Range: 12-66
52Unspecified8C: 2.28
R: 2.07
S: 2.02
I: 1.76
Grubbe, 2009Desloratadine 5 mg/Pseudoephedrine 240 mg20034.9
Range: 12-74
60.5White: 81
Black: 12
Hispanic: 4
Asian: 2
Other: 2
19.6
Range: 2-69
C: 2.47
Desloratadine 5 mg19837
Range: 12-76
65.2White: 77
Black: 13
Hispanic: 7
Asian: 2
Other: 2
17.9
Range: 2-56
C: 2.50
Pleskow, 2005Desloratadine 5 mg/Pseudoephedrine 240 mg37234
Range: 12-78
59.4White: 77
Black: 11
Hispanic: 8
Asian: 3
Other: <1
16.5
Range: 2-51
Desloratadine 5 mg37235
Range: 12-76
65.9White: 80
Black: 12
Hispanic: 7
Asian: <1
Other: 0
18.0
Range: 2-55
Schenkel, 2002Desloratadine 5 mg
Pseudoephedrine 240 mg
33634.264Unspecified17.5C: 2.56
Desloratadine 5 mg34034.860Unspecified18.3C: 2.57
Sussman, 1999Fexofenadrine 120 mg/Pseudoephedrine 240 mg21533.0 (11.41)
Range: 13-66
57.7White: 86.5
Black: 6.0
Asian: 5.6
Other: 1.9
14.9 (9.65)
Range: 2.0-55.0
C: 2.32 (SE: 0.03)
Fexofenadrine 120 mg21834.9 ( 12.35)
Range: 12-64
56.9White: 85.3
Black: 6.0
Asian: 8.3
Other: 0.5
15.2 (9.79)
Range: 2.0-46.2
C: 2.36 (SE: 0.03)

C = Congestion; I = itching; n= patients randomized to comparator groups of interest; NSS = nasal symptom score; R = rhinorrhea; S = sneezing, SE = standard error.

Values are presented as mean (standard deviation) unless otherwise noted.

a

Individual symptoms rated on a scale from 0 (no symptoms) to 3 (severe symptoms) in all cases except Sussman (1999) where the maximum was 4.

From: Appendix C, Evidence Tables

Cover of Treatments for Seasonal Allergic Rhinitis
Treatments for Seasonal Allergic Rhinitis [Internet].
Comparative Effectiveness Reviews, No. 120.
Glacy J, Putnam K, Godfrey S, et al.

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