Table 29Adjunctive therapies: Light therapy compared with standard wound care or sham light therapy

Author Year
Study Type
Quality
Number Enrolled/Completed
Setting
Pressure Ulcer StageaMean age (Range)
Sex
Population
FollowupOutcomes Measured and Treatment EffectBenefit:
Wound Improvement
Dehlin 2003208
Trial
Fair
N=198/164
8 geriatric centers inpatient/outpatient
Stage II–IV84 years (65–105)
Female: 65%
General
12 weeksComplete healing: 44% vs. 40%, p=0.93
Reduction ulcer size: p=0.18
Time until total healing: p=0.93

Harms related or possibly related to treatment: tingling (1); pain (2); bleeding (1); redness (1)
~
Dehlin 2007209
Trial
Fair
N=181/163
8 geriatric centers inpatient/ outpatient
Stage III84 years (65–105)
Female: 61%
General
12 weeksNormalized reduction in ulcer size at week 12: 0.79 vs. 0.50 (p=0.039)
Normalized weekly reduction in ulcer size over time 15.1% vs. 10.9% (p-value not reported)
Rate of normalized reduction in PU size (p=0.12)
Percent totally healed ulcers: 54.4% vs. 59.5%, (p=0.52)
Time to totally healed ulcers (p=0.58)
Harms possibly related to treatment: 9 patients in each group had skin symptoms (mainly tingling)
+
Durovic 2008210
Trial
Fair
N=48/40
NR
Stage I–III65 years (NR)
Female: 45%
General
4 weeksWound surface area change: 4.29 cm2 reduction (p=0.01) vs. 3.82 cm2 increase (p=0.001)

Harms : NR
+
Iordanou 2002211
Observational
Fair
N=55
Hospital
Stage I–IVAge: 67 years (37–85)
Sex: NR
General
2 weeksWound surface area change: 0.58 cm2 reduction (p≤0.001) vs. 0.06 cm2 reduction (p≤0.007)

Harms not reported
+
Schubert 2001212
Trial
Fair
N=67 / 59
Hospital
Stage II–IIIAge: 85 years (NR)
Female: 64%
General
10 weeksWound surface area per week: 29.8% vs. 20.0%; Healing rate: 49% higher for active group (p<0.05).

Harms: None
+

NPUAP = National Pressure Ulcer Advisory Panel; NR = not reported; NS = not significant; PU = pressure ulcer

a

Pressure ulcer stage indicates NPUAP staging unless otherwise noted. Non-NPUAP staging was converted to the equivalent NPUAP stage where possible.

++Complete wound healing.

+Some improvement in wound healing.

~No difference.

From: Results

Cover of Pressure Ulcer Treatment Strategies: Comparative Effectiveness
Pressure Ulcer Treatment Strategies: Comparative Effectiveness [Internet].
Comparative Effectiveness Reviews, No. 90.
Saha S, Smith MEB, Totten A, et al.

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