Table F-1Detailed strength of evidence grading table, tube retention

Intervention, Outcome, Time to OutcomeNumber of Studies; SubjectsRisk of BiasConsistencyDirectnessPrecisionStrength of Evidence Grade
Magnitude of Effect
TT v. TT + N-acetylcysteine addition, mean time1; 75MediumUnknown, single studyDirectImpreciseInsufficient, single small study, no difference
Shah Teflon tube +aspiration v. shah Teflon tube no aspiration, 3–24 mo1; 55MediumUnknown, single studyDirectImpreciseInsufficient, single small study, no difference
Permavent silicone Shah v. polyethelyne Shah, TT, 1 yr1; 25MediumUnknown, single studyDirectImpreciseInsufficient, single small study, no difference
Goode silicon TT v. Teflon Armstrong TT, 1 yr1; 15MediumUnknown, single studyDirectImpreciseInsufficient, single small study, no difference
Phosphorylcholine-coated fluoroplastic Armstrong TT v. uncoated Armstrong TT, 2 yrs1; 70MediumUnknown, single studyDirectImpreciseInsufficient, single small study, no difference
Goode silicon TT v. Teflon Armstrong TT, 3–5 yrs1; 15MediumUnknown, single studyDirectImpreciseInsufficient, single small study,

Abbreviations: TT = tympanostomy tubes; v. = versus.

From: Appendix F, Detailed Strength of Evidence Tables

Cover of Otitis Media With Effusion: Comparative Effectiveness of Treatments
Otitis Media With Effusion: Comparative Effectiveness of Treatments [Internet].
Comparative Effectiveness Reviews, No. 101.
Berkman ND, Wallace IF, Steiner MJ, et al.

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