Table 39On-study mortality: ESA versus control (GRADE evidence table)

Trials (N)Subjects (N)Risk of Bias Design/QualityConsistencyDirectnessPrecisionResults HR (95% CI); I2Overall Strength of Evidence
3711,266Mediuma trial quality
high-18; low-19
InconsistentDirectPrecise1.17 (1.04 to 1.31)
0%
Moderate

CI = confidence interval; HR = hazard ratio

a

No trial was powered to detect a survival difference

From: Results

Cover of Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment
Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment: Comparative Effectiveness Update [Internet].
Comparative Effectiveness Reviews, No. 113.
Grant MD, Piper M, Bohlius J, et al.

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