Table 2.

Cardiac Phenotype of Classic Timothy Syndrome

Cardiac PhenotypeAffected 1/Evaluated%Not Available
QTc prolongation25/251000
TWA7/107015
Functional 2:1 AV block17/21814
Tachyarrhythmias21/25840
Congenital heart disease
(PDA, PFO, VSD, TOF, HCM)
13/21614

TWA = T-wave alternance

PDA = patent ductus arteriosus

PFO = patent foramen ovale

VSD = ventricular septal defect

TOF = tetralogy of Fallot

HCM = hypertrophic cardiomyopathy

1.

n = 25 (13 males, 12 females)

From: Timothy Syndrome

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