Table 2EHC approach to identifying and managing bias in conducting SRs

Proxies for BiasCore Team in Authoring ReviewSolicited Input for Key QuestionsSolicited Input for ProtocolSolicited Input for Draft Report
Financial COIExclude if identifiedExclude or balance if necessary*Exclude or balance if necessary*Exclude if identified
Nonfinancial COI (professional affiliations)Balance if identifiedBalance if identifiedBalance if identifiedBalance if identified
Established beliefsAvoid or balance if identifiedBalance if identifiedBalance if identifiedBalance if identified
Involvement in study included in the reviewExclude or restrict role to refrain from grading own study at individual-study or body-of-evidence levelBalance if identifiedBalance if identifiedInclude and balance if identified
*

In some cases such as rare diseases, it may be difficult to find appropriate experts without financial affiliations. Input is limited to protocol development and not results analysis.

From: Results

Cover of EPC Response to IOM Standards for Systematic Reviews
EPC Response to IOM Standards for Systematic Reviews [Internet].
Lau J, Chang S, Berkman N, et al.

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