Table G-8Exposure-based therapy compared with cognitive processing therapy

Domains Pertaining to Strength of EvidenceMagnitude of EffectStrength of Evidence
Number of Studies; Number of SubjectsRisk of Bias; DesignConsistencyDirectnessPrecisionSummary Effect Size (95% CI)High, Moderate, Low, Insufficient
PTSD Symptom Reduction: CAPS
1; 124Medium; RCTNA, single studyDirectImpreciseWMD 3.97 (−5.95 to 13.9)Insufficient
Remission (no longer having symptoms)
0; 0NANANANANAInsufficient
Loss of Diagnosis
1; 124Medium; RCTNA, single studyDirectImpreciseRD 0.00 (−0.18 to 0.18)Insufficient
Prevention/reduction of comorbid depression: BDI
1; 124Medium; RCTNA, single studyDirectImpreciseWMD 2.94 (−0.75 to 6.63)Insufficient
Prevention/reduction of comorbid anxiety
0; 0NANANANANAInsufficient
Quality of Life
0; 0NANANANANAInsufficient
Disability/functional impairment
0; 0NANANANANAInsufficient
Return to work or return to active duty: % of subjects actively working at 6 month follow up
0; 0NANANANANAInsufficient

Abbreviations: CI = confidence interval; NA = not applicable; RCT = randomized controlled trial

From: Appendix G, Strength of Evidence

Cover of Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD)
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD) [Internet].
Comparative Effectiveness Reviews, No. 92.
Jonas DE, Cusack K, Forneris CA, et al.

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