Table 44Results of meta-analyses and risk difference calculations for specific adverse events: fluoxetine compared with placebo

OutcomeN TrialsN SubjectsRD95% CIHeterogeneity I2
Headache3a7760.03−0.04, 0.0928.2
Nausea2b7120.050.00, 0.090
Insomnia1b3010.03−0.06, 0.11NA
Diarrhea1c640.240.01, 0.47NA
Somnolence1d4110.050.00, 0.100

CI = confidence interval; N = number of trials or subjects contributing data; RD = risk difference

a

Studies included in meta-analysis: van der Kolk et al., 1994,162 Martenyi et al., 2006,160 Martenyi et al., 2007.161

b

Studies included in meta-analysis: Martenyi et al., 2006,160 Martenyi et al., 2007.161

c

Studies included in risk difference calculation: van der Kolk et al., 1994.162

d

Studies included in risk difference calculation: Martenyi et al., 2007.161

Note: Positive risk differences favor placebo.

From: Results

Cover of Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD)
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD) [Internet].
Comparative Effectiveness Reviews, No. 92.
Jonas DE, Cusack K, Forneris CA, et al.

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