Figure 3. . AP view of an adolescent showing relatively mild facial signs but with widely spaced eyes, mildly downslanted palpebral fissures, thick vermilion of the upper and lower lips, and small teeth.

Figure 3.

AP view of an adolescent showing relatively mild facial signs but with widely spaced eyes, mildly downslanted palpebral fissures, thick vermilion of the upper and lower lips, and small teeth. The columnella is broad but nares are a good size, perhaps reflecting an interracial difference in disease expression. (Affected individual has a known RPS6KA3 pathogenic variant.)

From: Coffin-Lowry Syndrome

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