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Cover of Future Research Needs for Noncyclic Chronic Pelvic Pain Therapies for Women

Future Research Needs for Noncyclic Chronic Pelvic Pain Therapies for Women

Identification of Future Research Needs From Comparative Effectiveness Review No. 41

Future Research Needs Papers, No. 19

Investigators: , MD, , MLIS, and , MD, FRCSC.

Vanderbilt Evidence-based Practice Center
Rockville (MD): Agency for Healthcare Research and Quality (US); .
Report No.: 12-EHC126-EF

Structured Abstract

Objectives:

The objective of this future research needs project is to identify high-priority research needs for noncyclic chronic pelvic pain in women. This report builds on the research needs and methodologic issues identified in the comparative evidence review published in January 2012.

Data Sources:

We recruited stakeholders to participate in a teleconference to identify a comprehensive list of research questions and methodologic recommendations for future research on noncyclic chronic pelvic pain. Stakeholders completed two Web-based surveys to prioritize research questions and recommendations. The first survey used a 5-point Likert scale to rate the overall importance of the research needs identified from the comparative effectiveness review and the stakeholder conference call. Stakeholders were then asked to rank the highest-rated research using a 5-point scale across six prespecified criteria modified from the Effective Healthcare Program criteria. We also searched U.S. and international trial registries to identify currently funded and recently completed research on therapies to treat noncyclic chronic pelvic pain.

Results:

Twelve stakeholders representing patient advocacy groups, academic research, obstetricians and gynecologists, the payor perspective, and national foundations agreed to participate. Stakeholder participation exceeded 50 percent throughout the project. In the first Web-based survey, stakeholders rated 63 research needs related to etiology, diagnosis, treatment and methodological issues. Using a cutoff of 4.3, survey results generated a listed 31 research questions to promote to the final prioritization survey. Seven stakeholders completed the prioritization survey to generate a list of high-priority research needs for noncyclic chronic pelvic pain. The top-tier research needs consisted of items with an overall score of at least 4.0 (n=6); the second-tier consisted of research needs with an overall score of 3.75–3.99 (n=9).

Conclusions:

We used a multistep process to identify and prioritize research questions to address specific knowledge gaps related to therapies for noncyclic chronic pelvic pain. The highest priority research questions encompass numerous topics related to noncyclic chronic pelvic pain, reflecting the ubiquity of gaps in the relevant literature.

Prepared for: Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services1, Contract No. 290-2007-10065-I, Prepared by: Vanderbilt Evidence-based Practice Center, Nashville, TN

Suggested citation:

Reynolds WS, Potter SA, Andrews JC. Future Research Needs for Noncyclic Chronic Pelvic Pain Therapies for Women. Future Research Needs Paper No. 19. (Prepared by the Vanderbilt Evidence-based Practice Center under Contract No. 290-2007-10065-I) AHRQ Publication No. 12-EHC126-EF. Rockville, MD: Agency for Healthcare Research and Quality. September 2012. www.effectivehealthcare.ahrq.gov/reports/final.cfm.

This report is based on research conducted by the Vanderbilt Evidence-based Practice Center (EPC) under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (Contract No. 290-2007-10065-I). The findings and conclusions in this document are those of the author(s), who are responsible for its contents; the findings and conclusions do not necessarily represent the views of AHRQ. Therefore, no statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services.

The information in this report is intended to help health care researchers and funders of research make well-informed decisions in designing and funding research and thereby improve the quality of health care services. This report is not intended to be a substitute for the application of scientific judgment. Anyone who makes decisions concerning the provision of clinical care should consider this report in the same way as any medical research and in conjunction with all other pertinent information, i.e., in the context of available resources and circumstances.

None of the investigators have any affiliation or financial involvement that conflicts with the material presented in this report.

1

540 Gaither Road, Rockville, MD 20850; www​.ahrq.gov

Bookshelf ID: NBK133323PMID: 23658938

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