Table 23Propiverine (before vs after treatment) - Clinical study characteristics and clinical summary of findings

No. of studiesDesignTreatment (n)Control (n)ResultsLimitationsInconsistencyIndirectnessImprecisionOther considerationsQuality
Outcome: 24hr Incontinence episodes mean (SD)
1 [A]ObservationalPropiverine N=46
Before treatment
After treatmentBefore vs after
Difference mean (SD) –1.6 (15.6); p<0.05
S (i)NNN (ii)NVery Low
Outcome: Maximum cystometric capacity
1 [A]ObservationalPropiverine N=46
Before treatment
After treatmentBefore vs after
Mean (SD) ml 198 (110) vs 309 (166) MD 111
S (i)NNN (ii)NVery Low
Outcome: Bladder compliance
1 [A]ObservationalPropiverine N=46
Before treatment
After treatmentBefore vs after
Mean (SD) ml/cm H2O 10.8 (13.8) vs 22.7 (24.3) MD 11.9
S (i)NNN (ii)NVery low
Outcome: Residual urine
1 [A]ObservationalPropiverine N=46
Before treatment
After treatmentBefore vs after
Mean (SD) ml 72.6 (115) vs 140.9 (167) MD 68.3
S (i)NNN (ii)NVery low

S serious N none MD mean difference CI confidence interval RR relative risk

i

Before vs after data

ii

Imprecision not assessed, data at high risk of bias

[A]

Stohrer et al. (2007)47

From: 8, Treatment to improve bladder storage

Cover of Urinary Incontinence in Neurological Disease
Urinary Incontinence in Neurological Disease: Management of Lower Urinary Tract Dysfunction in Neurological Disease.
NICE Clinical Guidelines, No. 148.
National Clinical Guideline Centre (UK).
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