First-line
90% Laparoscopic salpingotomy first-line£1392 × 0.9 = £1252.80
Of which:
 Surgical complications£1333 × 0.9 × 0.004 = £4.80
 Blood transfusion£297 × 0.9 × 0.009 = £2.41
10% Open salpingotomy first-line£2218 × 0.1 = £221.80
Of which:
 Surgical complications£1333 × 0.1 × 0.036 = £4.80
 Blood transfusion£297 × 0.1 × 0.071 = £2.11
20.61% fail salpingotomy first-line
Of which:
 Emergency admission£789 × 0.2061 × 0.1 = £16.26
Second-line
7.21% Methotrexate second-line£425 × 0.0721 = £30.64
12.06% Laparoscopic salpingectomy second-line£1,392 × 0.1206 = £167.88
Of which:
 Surgical complications£1333 × 0.1206 × 0.004 = £0.64
 Blood transfusion£297 × 0.1206 × 0.009 = £0.32
1.34% Open salpingectomy second-line£2218 × 0.0134 = £29.72
Of which:
 Surgical complications£1333 × 0.0134 × 0.036 = £0.64
 Blood transfusion£297 × 0.0134 × 0.071 = £0.28
1.49% fail methotrexate second-line
Of which:
 1.34% Laparoscopic salpingectomy third-line£1,392 × 0.0134 = £18.65
  Of which:
  Surgical complications£1333 × 0.0134 × 0.004 = £0.07
  Blood transfusion£297 × 0.0134 × 0.009 = £0.04
 0.15% Open salpingectomy third-line£2,218 × 0.0015 = £3.33
  Of which:
  Surgical complications£1333 × 0.0015 × 0.036 = £0.07
  Blood transfusion£297 × 0.0015 × 0.071 = £0.03
Follow-up
79.4% Salpingotomy follow-up
 Full blood count£3.94 × 0 × 0.794 = £0
 Serum hCG£3.94 × 3 × 0.794 = £9.39
 Kidney function£3.60 × 0 × 0.794 = £0
 Liver function£4.72 × 0 × 0.794 = £0
 Urine pregnancy test£1 × 1 × 0.794 = £0.79
 GP visit£36 × 0 × 0.794 = £0
 Clinic visit£141 × 3 × 0.794 = £335.86
5.7% Salpingotomy/methotrexate follow-up
 Full blood count£3.94 × 1 × 0.057 = £0.22
 Serum hCG£3.94 × 5 × 0.057 = £1.12
 Kidney function£3.60 × 1 × 0.057 = £0.21
 Liver function£4.72 × 2 × 0.057 = £0.54
 Urine pregnancy test£1 × 1 × 0.057 = £0.06
 GP visit£36 × 0 × 0.057 = £0
 Clinic visit£141 × 5 × 0.057 = £40.19
13.4% Salpingotomy/salpingectomy follow-up
 Full blood count£3.94 × 0 × 0.134 = £0
 Serum hCG£3.94 × 2 × 0.134 = £1.06
 Kidney function£3.60 × 0 × 0.134 = £0
 Liver function£4.72 × 0 × 0.134 = £0
 Urine pregnancy test£1 × 1 × 0.134 = £0.13
 GP visit£36 × 0.5 × 0.134 = £2.41
 Clinic visit£141 × 2.5 × 0.134 = £47.24
1.5% Salpingotomy/methotrexate/salpingectomy follow-up
 Full blood count£3.94 × 1 × 0.015 = £0.06
 Serum hCG£3.94 × 3 × 0.015 = £0.18
 Kidney function£3.60 × 1 × 0.015 = £0.05
 Liver function£4.72 × 2 × 0.015 = £0.14
 Urine pregnancy test£1 × 1 × 0.015 = £0.02
 GP visit£36 × 0.5 × 0.015 = £0.27
 Clinic visit£141 × 3.5 × 0.015 = £7.40
Average weighted cost of salpingotomy =£2205

From: 10, Health economics

Cover of Ectopic Pregnancy and Miscarriage
Ectopic Pregnancy and Miscarriage: Diagnosis and Initial Management in Early Pregnancy of Ectopic Pregnancy and Miscarriage.
NICE Clinical Guidelines, No. 154.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG; 2012 Dec.
Copyright © 2012, National Collaborating Centre for Women's and Children's Health.

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