Table 4PCA3/DD3 assay characteristics

Authora, YearAttentive Massage UsedSpecimenMethod UsedAssay SpecifiedReporting UnitsHouse-keeping GeneHandling Temperatures Holding (C); Storage (C)Informative Results %
Adam90, 2011YesUUTMAProgensaPCA3 ScorePSANR98
Aubin91, 2010YesUUTMA“Gen-Probe”PCA3 ScorePSANR; -7094
Auprich92, 2011YesUUTMAProgensaPCA3 ScorePSANRNR
Auprich112, 2011YesUUTMAProgensaPCA3 ScorePSANR100
Bollito93, 2012YesUUTMAProgensaPCA3 ScorePSANR96
de la Taille95, 2011YesUUTMAProgensaPCA3 ScorePSANR99
Deras96, 2008YesUUTMAProgensaPCA3 ScorePSANR; -70100
FDA Summary Document97, 2012YesUUTMAProgensaPCA3 ScorePSANR93
Feero98, 2012YesUUTMAProgensaPCA3 ScorePSANRNR
Goode99, 2012YesUUTMAProgensa reagents by BostwickPCA3 ScorePSANR100
Hessels100, 2010YesUSTMAAptimaPCA3 ScorePSANR96
Liss114, 2011YesUUTMANRPCA3 ScorePSA2-8; NR100
Nakanishi115, 2008YesUUTMA“Gen-Probe”PCA3 ScorePSA2-8; -70100
Nyberg102, 2010YesUUTMAProgensaPCA3 ScorePSANR100
Ochiai103, 2011YesUUTMAAptimaPCA3 ScorePSANR; -70100
Perdona31, 2011YesUUTMAProgensaPCA3 ScorePSANR100
Ploussard116, 2011YesUUTMAProgensaPCA3 ScorePSANRNR
Roobol108, 2010YesUUTMAProgensaPCA3 ScorePSANR100
Schilling109, 2010YesUUTMA“Gen-Probe”PCA3 ScorePSANR99
Tosoian89, 2010YesUUTMAAptimaPCA3 ScorePSANR; -8098
Vlaeminck-Guillem118, 2011YesUUTMAProgensaPCA3 ScorePSANR100
Wang110, 2009YesUUTMA“Gen-Probe”PCA3 ScorePSA30; NR97
Whitman119, 2008YesUUTMA“Gen-Probe”PCA3 ScorePSANR100
Fradet85, 2004YesUUNASBAuPM3ProbabilityPSANR; 2-886
Tinzl86, 2004YesUUNASBAuPM3PCA3 ScorePSA4; -2079
Wu111, 2012YesUUTMAPCA3Plus by BostwickPCA3 ScorePSANRNR
Cao94, 2011YesUSQRT-PCRNRPCA3 ScorePSA4; -2092
Kusuda88, 2011NRLNQRT-PCRNRQuantificationGADPHNRNR
Mearini101, 2009YesUSQRT-PCRNRQuantificationBeta actinNR -70NR
Ouyang104, 2009YesUSQRT-PCRNRPCA3 ScoreGADPHNR; -8087
Rigau107, 2010YesUSQRT-PCRNRPCA3 ScorePSANR; -8082
Ankerst65, 2008NRNRNRNRbPCA3 ScorePSANRNR
Ploussard106, 2010NRUUNRNRcPCA3 ScorePSANRNR

LN = lymph node tissue; NASBA = nucleic acid sequence-based amplification; NR = not reported; QRTPCR = quantitative real time polymerase chain reaction; TMA = transcription-mediated amplification; U = urine unsedimented; US = urine sedimented.


Studies are in alphabetical order by methodology.


Ankerst analyzed data from a study concurrently reported by Haese et al., 200882. Haese indicated that PCA3 testing was done using Progensa.


This paper did not specify the PCA3 assay used, but two authors (van Poppel, de la Taille) disclosed an advisor and investigator relationship with GenProbe, making it likely that Progensa was the assay used.

From: Results

Cover of PCA3 Testing for the Diagnosis and Management of Prostate Cancer
PCA3 Testing for the Diagnosis and Management of Prostate Cancer [Internet].
Comparative Effectiveness Reviews, No. 98.
Bradley LA, Palomaki G, Gutman S, et al.

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