Appendix D. Table 9Summary of traditional meta-analysis results for HUI cognition from CCHS-CLSA and Buschke free from CSHA and NuAge

Method of Statistical HarmonizationAdjustmentSummary Effect Estimate (95% CI)I2Q*p-value
Raw Data – Using Hedge’s GUnadjusted0.15 (−0.06, 0.36)0.9020.62<0.001
Unadjusted (Including Participants with Complete Data for Covariates)0.15 (−0.05, 0.35)0.8816.54<0.001
Study-Specific Statistically Significant Covariates0.11 (−0.08, 0.30)0.8816.56<0.001
Common Set of Covariates0.12 (−0.07, 0.31)0.8614.530.001
T-Score – Weighted Mean DifferenceUnadjusted1.30 (−0.52, 3.12)0.8714.850.001
Unadjusted (Including Participants with Complete Data for Covariates)1.32 (−0.48, 3.11)0.8512.910.002
Common Set of Covariates1.24 (−0.77, 3.25)0.8714.960.001
C-Score – Weighted Mean DifferenceUnadjusted0.15 (−0.04, 0.35)0.8918.70<0.001
Unadjusted (Including Participants with Complete Data for Covariates)0.15 (−0.03, 0.34)0.8714.880.001
Common Set of Covariates0.12 (−0.06, 0.30)0.8513.100.001
*

All Q Statistics have 2 degrees of freedom

T-Scores minimally adjusted for age, sex and education level

Abbreviations: CI = confidence interval

From: Appendix D, Meta-Analysis Results Weighted Mean Difference Analysis

Cover of Harmonization of Cognitive Measures in Individual Participant Data and Aggregate Data Meta-Analysis
Harmonization of Cognitive Measures in Individual Participant Data and Aggregate Data Meta-Analysis [Internet].
Griffith L, van den Heuvel E, Fortier I, et al.

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