Table 17Summary of relationship of raw scores for cognitive measures with variables of interest

VariableCCHS-CLSA n=7,107CSHA n=1,730NuAge n=432
ReyHUIReyBUSC1BUSC_TBUSC1BUSC_T
Age in years (n)7,1067,1041,4971,7301,730432432
 Intercept11.83546.47957.099013.681315.342913.382718.3016
 Beta−0.0981−0.0151−0.0463−0.0938−0.0542−0.0819−0.0578
 R-square0.08690.00730.03320.06150.03910.01840.0113
 p-value<0.0001<0.0001<0.0001<0.0001<0.00010.00480.0269
Gender (n)7,1067,1041,4971,7301,730432432
 Intercept4.27565.37903.29686.305011.25236.670013.6350
 Beta (Ref: male)0.6503−0.00890.1876−0.1629−0.36671.26100.7572
 R-square0.02720.000020.00270.00090.00870.06920.0310
 p-value<0.00010.72030.04420.21330.0001<0.00010.0002
Highest level of education (n)7,0607,0581,4881,7191,719432432
 Intercept3.76755.26013.10016.273511.01906.909113.6515
 Beta (Ref: Low (0–8)
 Moderate (9–13)0.78430.08860.4733−0.1492−0.00150.40060.3079
 High (14+)1.36010.18280.8941−0.15750.07380.65300.6384
 R-square0.06600.0040.03130.00070.00020.00840.0110
 p-value<0.0001<0.0001<0.00010.52710.87730.16320.0939
Country of birth (n)7,1047,1021,4971,7301,730432432
 Intercept4.46985.35053.20766.049610.89727.4000014.2000
 Beta (Ref: other country)0.22350.02890.30950.22740.1860−0.0589−0.1767
 R-square0.00200.00010.00700.00160.00210.00010.0006
 p-value0.00020.35980.00120.09220.05710.87590.6018
Ever/current alcohol consumption (n)7,1067,1041,2971,5071,507432432
 Intercept4.24965.36803.44436.256211.01206.000013.5714
 Beta (Ref: never)0.43560.00630.06430.00540.12171.41610.4943
 R-square0.00360.0000030.00020.00000.00070.01620.0025
 p-value<0.00010.89070.58530.97360.29820.00800.3041
Standing height in centimeter (n)7,0707,0681,3861,6001,600432432
 Intercept6.92175.29082.92753.97358.928612.140914.8455
 Beta−0.01360.00100.00320.01410.0132−0.0297−0.0050
 R-square0.00460.00010.00030.00280.00480.01310.0005
 p-value<0.00010.42920.49940.03410.00550.01720.6574
Weight in Kg7,0006,9981,4281,6541,654432432
 Intercept4.76165.32393.16314.705910.05079.138614.2068
 Beta−0.00140.00070.00400.02350.0152−0.0246−0.0023
 R-square0.00010.00010.00100.01540.01210.02240.0002
 p-value0.33890.37800.2332<0.0001<0.00010.00180.7502
Body mass index (n)6,9686,9661,3651,5761,576432432
 Intercept4.35085.35713.29844.868210.39568.698514.0952
 Beta0.00120.00070.00630.05750.0273−0.0486−0.0019
 R-square0.00080.000010.00030.01010.00440.00870.0000
 p-value0.01650.77840.5477<0.00010.00810.05290.9320
Occurrence of high blood pressure(n)7,1047,1021,3581,5611,561432432
 Intercept4.73175.38513.44696.154210.99267.491214.0354
 Beta (Ref: never)−0.1427−0.0191−0.05630.16990.1198−0.30180.0131
 R-square0.00130.000080.00020.00100.00100.00400.0000
 p-value0.00220.43970.56500.21440.21680.19050.9494
Occurrence of diabetes (n)7,1047,1021,4641,6911,691432432
 Intercept4.72535.38733.42696.195510.98637.336714.0077
 Beta (Ref: never)−0.4169−0.0746−0.11440.03260.19790.11330.3673
 R-square0.00670.00080.00050.00000.00120.00020.0025
 p-value<0.00010.02020.39940.86240.14840.77580.3032
Occurrence of myocardial infarction (n)7,0927,0901,4401,6651,665424424
 Intercept4.71965.38893.44596.212611.00577.288814.0327
 Beta (Ref: never)−0.5404−0.1138−0.14900.12580.25280.50060.1077
 R-square0.00830.00130.00100.00030.00250.00510.0003
 p-value<0.00010.00230.23910.47400.04340.14360.7234
Categorical indicator of the participants level of physical activity using CSHA categories7,1067,10412,791,4841,484432432
 Intercept4.29635.2983.20585.785510.82617.587014.1739
 Beta (Ref: none)
 Low level0.1992−0.06510.43660.64800.3512−0.00920.3816
 Moderate or high level0.45780.11400.57141.10090.4862−0.3025−0.2179
 R-square0.00820.00390.02310.03570.01410.00260.0076
 p-value<0.0001<0.0001<0.0001<0.0001<0.00010.57370.1928
Categorical indicator of the participants level of physical activity using CSHA categories (4 categories) (n)7,1067,1041,2791,4841,484432432
 Intercept4.29635.29803.20585.785510.82617.587014.1739
 Beta (Ref: none)
 Low level0.1992−0.06510.43660.64800.3512−0.00920.3816
 Moderate level0.38340.09750.50800.97440.3902−0.1623−0.1830
 High level0.69090.16560.78451.52150.8054−0.5542−0.2805
 R-square0.01150.00450.02460.03820.01690.00750.0080
 p-value<0.0001<0.0001<0.0001<0.0001<0.00010.36020.3274

BUSC1 = BUSC 1st recall; BUSC_T = BUSC total recall; CCHS = Canadian Community Health Survey; CLSA = Canadian Longitudinal Study on Aging; CSHA = Canadian Study of Health and Aging; HUI = Health Utilities Index; kg = kilograms; n= sample size; NuAge = Quebec Longitudinal Study on Nutrition and Aging

From: Methods and Results: Implementing and Evaluating Three Methods of Statistical Harmonization Applied to Cognitive Measures (Objective 3)

Cover of Harmonization of Cognitive Measures in Individual Participant Data and Aggregate Data Meta-Analysis
Harmonization of Cognitive Measures in Individual Participant Data and Aggregate Data Meta-Analysis [Internet].
Griffith L, van den Heuvel E, Fortier I, et al.

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