Table 19gSummary of traditional meta-analysis results for HUI cognition from CCHS-CLSA, Rey from CSHA, and Buschke Free from NuAge using Hedges’ g

Method of Statistical HarmonizationAdjustmentSummary Effect Estimate (95% CI)I2Q*p-value
Raw DataUnadjusted0.13 (−0.02, 0.28)0.809.860.007
Unadjusted (Including Participants with Complete Data for Covariates)0.13 (−0.02, 0.27)0.758.100.02
Study-Specific Statistically Significant Covariates0.09 (−0.04, 0.22)0.747.580.02
Common Set of Covariates0.09 (−0.03, 0.22)0.665.830.054
T-ScoreUnadjusted0.11 (−0.01, 0.22)0.665.90.051
Unadjusted (Including Participants with Complete Data for Covariates)0.11 (−0.002, 0.21)0.574.630.099
Common Set of Covariates0.09 (−0.03, 0.22)0.665.830.054
C-ScoreUnadjusted0.13 (−0.02, 0.28)0.809.860.01
Unadjusted (Including Participants with Complete Data for Covariates)0.13 (−0.02, 0.27)0.758.100.02
Common Set of Covariates0.10 (−0.03, 0.22)0.665.830.054

CCHS = Canadian Community Health Survey; CI = confidence interval; CLSA = Canadian Longitudinal Study on Aging; CSHA = Canadian Study of Health and Aging; NuAge = Quebec Longitudinal Study on Nutrition and Aging

*

All Q Statistics have 2 degrees of freedom.

T-Scores minimally adjusted for age, sex and education level.

From: Methods and Results: Implementing and Evaluating Three Methods of Statistical Harmonization Applied to Cognitive Measures (Objective 3)

Cover of Harmonization of Cognitive Measures in Individual Participant Data and Aggregate Data Meta-Analysis
Harmonization of Cognitive Measures in Individual Participant Data and Aggregate Data Meta-Analysis [Internet].
Griffith L, van den Heuvel E, Fortier I, et al.

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