Table 1: Uptake of radioactivity from [64Cu]DO3A-xy-ACR in various tissues of athymic mice bearing U87MG cell tumors at different time points.

TissuesAccumulated radioactivity (% ID/g) at different time points p.i.
0.5 h1 h2 h4 h24 h
Blood0.90 ± 0.220.60 ± 0.170.70 ± 0.080.70 ± 0.190.53 ± 0.05
Heart0.66 ± 0.250.66 ± 0.080.70 ± 0.110.89 ± 0.131.14 ± 0.33
Kidney2.89 ± 0.902.53 ± 0.372.63 ± 0.422.18 ± 0.392.38 ± 0.41
Liver31.90 ± 3.9824.95 ± 5.6415.20 ± 4.2914.09 ± 6.828.18 ± 1.27
Muscle0.29 ± 0.180.24 ± 0.110.20 ± 0.130.33 ± 0.060.34 ± 0.17
Tumor1.07 ± 0.231.58 ± 0.552.71 ± 0.663.47 ± 1.193.52 ± 1.72

For complete data, see Zhou et al. (9).

From: 64Cu-Labeled 2,6-bis(dimethylamino)-10-(4-((4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclodo-decan-1-yl)methyl)benzyl)-acridin-10-ium

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