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Harris B, Andrews PJD, Murray GD, et al. Systematic Review of Head Cooling in Adults After Traumatic Brain Injury and Stroke. Southampton (UK): NIHR Journals Library; 2012 Nov. (Health Technology Assessment, No. 16.45.)

Cover of Systematic Review of Head Cooling in Adults After Traumatic Brain Injury and Stroke

Systematic Review of Head Cooling in Adults After Traumatic Brain Injury and Stroke.

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2Aim and objectives

The aim of this review was to assess the effectiveness and cost-effectiveness of non-invasive head cooling in adults after TBI and stroke and provide a comprehensive assessment of head-cooling research in these patients.

The objectives were:

  1. Assessment of temperature change To assess what effect non-invasive head cooling has on intracranial temperature and/or core trunk temperature in patients after TBI and stroke. This objective was informed by studies in cardiac arrest as well as those in TBI and stroke.
  2. Assessment of head cooling on outcome To assess what impact non-invasive head cooling has on disability, assessed with a validated outcome score, and mortality in adults after TBI and stroke.
  3. Complications associated with head cooling To determine any adverse effects or complications associated with head cooling or the specific devices and methods used. Studies in TBI, stroke, cardiac arrest and neonatal HIE all provided information for this objective.
  4. Health economic assessment To assess the cost-effectiveness of head cooling in TBI and stroke.
  5. Public involvement To present the results of the review to members of the general public, in order to hear their views on the concept and possible use and effectiveness of head cooling, and provide information on their views for clinicians and researchers planning to use or trial head cooling.
© 2012, Crown Copyright.

Included under terms of UK Non-commercial Government License.

Bookshelf ID: NBK127497

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