[111In]-DOTA peptideAccumulated radioactivity (% of injected dose/gram tissue)Tumor/blood ratio
BloodPancreasKidneyStomachTumor
sCCK80.03 ± 0.01
(0.02 ± 0.01)*
2.01 ± 0.28
(0.24 ± 0.03)
1.70 ± 0.17
(1.80 ± 0.16)
0.69 ± 0.05
(0.17 ± 0.03)
4.78 ± 0.64
(1.90 ± 0.16)
189.64 ± 61.26
(91.12 ± 20.34)
sCCK8[Phe2(p-CH2SO3H)]0.02 ± 0.01
(0.02 ± 0.00)
3.17 ± 0.74
(0.28 ± 0.03)
1.40 ± 0.05
(1.58 ± 0.35)
0.79 ± 0.06
(0.47 ± 0.19)
2.18 ± 0.36
(0.58 ± 0.28)
125.87 ± 51.68
(33.55 ± 16.00)
sCCK8[Phe2(p-CH2SO3H),HPG3,6]0.04 ± 0.01
(0.06 ± 0.00)
1.23 ± 0.14
(0.19 ± 0.16)
1.48 ± 0.16
(2.03 ± 0.22)
0.41 ± 0.05
(0.11 ± 0.04)
1.92 ± 0.31
(0.44 ± 0.15)
48.43 ± 12.01
(7.32 ± 2.91)
sCCK8[Phe2(p-CH2SO3H),Nle3,6]0.03 ± 0.00
(0.03 ± 0.00)
2.84 ± 0.19
(0.31 ± 0.08
1.35 ± 0.24
(1.53 ± 0.29)
0.84 ± 0.14
(0.25 ± 0.02)
4.54 ± 1.15
(1.40 ± 0.20)
157.08 ± 35.42
(50.68 ± 5.97)

From: 111In-Labeled DOTA-conjugated sCCK8[Phe2(p-CH2SO3H),Nle3,6], a sulfated cholecystokinin 8 (sCCK8) peptide derivative

Cover of Molecular Imaging and Contrast Agent Database (MICAD)
Molecular Imaging and Contrast Agent Database (MICAD) [Internet].

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