Table 15Short-term testicular descent in two-arm, randomized, placebo-controlled studies

Study
N
Length of Followup
Quality
LHRH DoseLHRH FrequencyLHRH DurationLHRH Descent (%)Placebo Descent (%)
Olsen et al., 199219
N = 123
4 weeks
Fair
400μg3 times daily4 weeks9.71.6a
De Muinck Keizer-Schrama and Hazebroek et al., 1986–198723, 24, 25
N = 237
8 weeks
Poor
200μg3 times daily4 weeks9.08.0
Hagberg and Westphal, 198227
N = 50
4 weeks
Poor
100μg3 times daily28 days62.03.0
Karpe et al., 198329
N = 50
6 months
Poor
100μg6 times daily28 days20.012.0
Wit et al., 198630
N=49
8 weeks
Poor
400μg3 times daily28 days3718

CI = confidence interval; LHRH = luteinizing hormone releasing hormone; N = number

a

Statistical significance was reported only for this comparison—p=0.12 (95% CI, 0.1 to 16.6).

From: Results

Cover of Evaluation and Treatment of Cryptorchidism
Evaluation and Treatment of Cryptorchidism [Internet].
Comparative Effectiveness Reviews, No. 88.
Penson DF, Krishnaswami S, Jules A, et al.

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