TABLE 3Advantages and disadvantages of TCD ultrasonography

AdvantageDisadvantage
Can be performed at the bedsideOperator dependent, so requires skill and experience in interpretation
Gives immediate information as to intracerebral vasculatureCan be technically difficult owing to poor acoustic window
Can be easily repeatedAllows for examination of cerebral blood volume only in certain segments of large intracranial vessels
Less expensive than other techniques, such as magnetic resonance imagingDetects indirect effects (such as abnormal waveform characteristics) of lesions
Does not use contrast agents, therefore avoiding allergic reactions and decreasing patient riskDoes not detect silent infarcts
High temporal resolutionDoes not detect all children who are at increased risk of stroke
Safe and non-invasive procedure

From: 2, Background

Cover of The Clinical Effectiveness and Cost-Effectiveness of Primary Stroke Prevention in Children with Sickle Cell Disease: A Systematic Review and Economic Evaluation
The Clinical Effectiveness and Cost-Effectiveness of Primary Stroke Prevention in Children with Sickle Cell Disease: A Systematic Review and Economic Evaluation.
Health Technology Assessment, No. 16.43.
Cherry MG, Greenhalgh J, Osipenko L, et al.
Southampton (UK): NIHR Journals Library; 2012 Nov.
© 2012, Crown Copyright.

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