This figure is a flow chart that summarizes the search and selection of articles related to screening for hepatitis C virus infection in asymptomatic adults, as well as articles realted to screening for hepatitis C virus infection in pregnant women. Citations were identified through bibliographnic databases, including CCRCT, CDSR, MEDLINE, Scopus, and PsychINFO, as well as through other sources, including experts, reference lists and gray literature. For screening for hepatitis C virus infection in asymptomatic adults: there were 8,206 abstracts of potentially relevant articles reviewed along with 36 articles included in the previous report. After removing 156 duplicates and 7,725 abstracts that were not relevant to key questions, a set of 289 articles was identified for full text review. Of those 289 full text articles reviewed, 161 were excluded for the following reasons: wrong population, wrong intervention, wrong outcomes, wrong study design for key question, no original data, not English language, or not relevant. Of the 289 full text articles reviewed, 128 were intially included, along with 77 additional studies found through reference list searches and peer review. After reviewing additional studies, a final total of 166 studies were included in the review of hepatitis C virus infection in asymptomatic adults (of the additional studies found through peer review and public comment, all 39 were excluded). For screening in pregnant women, there were 2,580 abstracts of potentially relevant articles reviewed. After removing 81 duplicates and excluding 2,055 abstracts that were not relevant to key question 7, a set of 444 articles was identified for full text review. Of those 444 articles, 416 were excluded for the following reasons: wrong population, wrong intervention, wrong outcomes, wrong study design for key question, no original data, not English language, or not relevant. Of the 444 full text articles reviewed, 17 are included in the review. The articles found for each key question were: none for Key Question 1, none for Key Question 2a, 5 for Key Question 2b, 5 for Key Question 3, 135 articles for Key Question 4a, 3 articles for Key Question 4b, 6 articles for Key Question 5, 1 article for Key Question 6a, 5 articles for Key question 6b, 4 articles for Key Question 6c, and 17 articles for Key Question 7.

Figure 2Study flow diagram: Screening for hepatitis C virus infection in asymptomatic adults and pregnant women

a Includes studies found through Peer Review and Public Comment.

b One study used for two Key Questions.

c One study resulting in two publications.

From: Results

Cover of Screening for Hepatitis C Virus Infection in Adults
Screening for Hepatitis C Virus Infection in Adults [Internet].
Comparative Effectiveness Reviews, No. 69.
Chou R, Cottrell EB, Wasson N, et al.

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