Figure 27. . Left, cartoon of a ribbon synapse at a salamander ON bipolar synapse.

Figure 27.

Left, cartoon of a ribbon synapse at a salamander ON bipolar synapse. Docked vesicles, release sites, transporters and postsynaptic receptors are indicated. Right, voltage clamp recordings (VH= −70 mV) from a salamander ganglion cell postsynaptic to an ON bipolar cell show rapid inward events (EPSCs) as large as 50 pA, as well as baseline fluctuations, suggesting that both fast and slow events contribute to the responses. NBQX, a selective antagonist for AMPA and KA receptors, eliminates most large spontaneous events but the addition of D-AP7 (NMDA specific antagonist) is needed to eliminate the small amplitude events. The illustration is from Miller et al., 2001 (221).

From: Bipolar Cell Pathways in the Vertebrate Retina

Cover of Webvision
Webvision: The Organization of the Retina and Visual System [Internet].
Kolb H, Fernandez E, Nelson R, editors.
Salt Lake City (UT): University of Utah Health Sciences Center; 1995-.

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