[Table], Possible Side Effects of DMARDs - Comparative Effectiveness Review Summary Guides for Consumers

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Comparative Effectiveness Review Summary Guides for Consumers [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2005-.

This publication is provided for historical reference only and the information may be out of date.

This publication is provided for historical reference only and the information may be out of date.

Comparative Effectiveness Review Summary Guides for Consumers [Internet].

Nonbiologic DMARDs	Biologic DMARDs
Upset stomach Nausea Diarrhea Hair loss Mouth sores Rash or serious skin reactions Liver, kidney, or lung problems	Redness, swelling, itching, bruising, or pain in the area where the shot was given Sinus infection (sore throat, runny nose, hoarseness) Headache Nausea Diarrhea
Possible Serious Side Effects
In rare cases, the nonbiologic DMARD methotrexate and some biologic DMARDs (including adalimumab [Humira^®], etanercept [Enbrel^®], golimumab [Simponi^®], and infliximab [Remicade^®]) have been associated with: Serious infections such as tuberculosis (called “TB”), fungal infections such as yeast, pneumonia, or food-borne illnesses such as listeria Cancer, usually lymphoma (cancer in the lymph glands, which are part of the immune system) The risk of serious infections or cancer is increased by taking two or more biologic DMARDs together or by taking a biologic DMARD with a nonbiologic DMARD. The exact risk to people with RA who are taking a DMARD is not known. Rituximab (Rituxan^®) can cause a severe reaction the first time you take it. It could also cause a life-threatening rash.

: This information comes from the U.S. Food and Drug Administration (FDA) labels of these medicines.

Cite this Page
John M. Eisenberg Center for Clinical Decisions and Communications Science. Medicines for Rheumatoid Arthritis: A Review of the Research for Adults. 2012 Nov 20. In: Comparative Effectiveness Review Summary Guides for Consumers [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2005-. [Table], Possible Side Effects of DMARDs.
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[Table], Possible Side Effects of DMARDs - Comparative Effectiveness Review Summ...
[Table], Possible Side Effects of DMARDs - Comparative Effectiveness Review Summary Guides for Consumers

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