Figure 14. Light micrographs and drawing illustrating regenerated retinal fibers in the stratum griseum superficiale of 40-μm-thick cryostat sections of the midbrain 48 weeks after grafting a segment of PN between the left eye and the lateral side of the ipsilateral SC and 5 days after intraocular injection of CTB.

Figure 14

Light micrographs and drawing illustrating regenerated retinal fibers in the stratum griseum superficiale of 40-μm-thick cryostat sections of the midbrain 48 weeks after grafting a segment of PN between the left eye and the lateral side of the ipsilateral SC and 5 days after intraocular injection of CTB. A, single regenerated RGC axon in the SGS of the SC forming many branches that bear multiple varicosities of similar appearance and uniform size. Scale bar, 10 μm. Inset illustrates a drawing of the midbrain section and indicates the region photographed. Scale bar, 1 mm. The stem axon is indicated by an arrowhead. B, high-power reconstruction of the terminal arbor in A. Scale bar, 9 μm. C, close interrelation between terminal cluster of bouton-like endings of regenerated retinal projections and SC neurons. Scale bar, 8 μm. From Aviles-Trigueros et al. (23).

From: Regeneration in the Visual System of Adult Mammals

Cover of Webvision
Webvision: The Organization of the Retina and Visual System [Internet].
Kolb H, Fernandez E, Nelson R, editors.
Salt Lake City (UT): University of Utah Health Sciences Center; 1995-.

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