Figure 54 is a metagraph comparing the effect on birthweight as a continuous outcome between women treated for GDM and those who were untreated. Five RCTs contributed data from 2,670 patients. Pooled results significantly favored the treatment group (MD -120.81, 95% CI, -163.40, -78.23; I²=2%). Two cohort studies contributed data from 515 participants; however results were not pooled due to substantial heterogeneity (I²=77%). Results for the individual studies were: Adams 1998 MD -354.8 (95%CI, -708.25, -1.35) and Fassett 2007 MD 87.30 (95%CI, -126.21, 300.81).

Figure 54Effect of treatment on outcomes for offspring of women with GDM: birthweight (continuous)

CI = confidence interval; GDM = gestational diabetes mellitus; IV = inverse variance; RCT = randomized controlled trial; SD = standard deviation

From: Results

Cover of Screening and Diagnosing Gestational Diabetes Mellitus
Screening and Diagnosing Gestational Diabetes Mellitus.
Evidence Reports/Technology Assessments, No. 210.
Hartling L, Dryden DM, Guthrie A, et al.

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