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National Research Council (US) and Institute of Medicine (US) Committee on State of the Science of Nuclear Medicine. Advancing Nuclear Medicine Through Innovation. Washington (DC): National Academies Press (US); 2007.

Cover of Advancing Nuclear Medicine Through Innovation

Advancing Nuclear Medicine Through Innovation.

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CCommercially Available Radiopharmaceuticals

Radiopharmaceutical Trade Name Primary Uses
Carbon-14 Urea Pytest Detection of H Pylori
Cobalt-57 cyanocobalamin Rubratope Schilling test
Chromium-51 sodium chromate Chromitope (Bracco)Mallinckrodt Cr-51 Labeling red blood cells (RBC)
Fluorine-18-FDG Positron emission tomography (PET) imaging
Gallium-67 Neoscan (GE)DuPont Ga-67Mallinckrodt Ga-67 Soft-tissue tumor and inflammatory process imaging
Indium-111 chloride Indiclor (Nycomed)Mallinckrodt In-111Cl Labeling monoclonal antibodies and peptides (OncoScint & Octreoscan)
Indium-111 pentetate (DTPA) Indium DTPA In-111 Imaging of cerebrospinal fluid kinetics
Indium-111 oxyquinoline (oxine) Indium-111 oxine Labeling leukocytes and platelets
Indium-111 Capromab pendetide ProstaScint Monoclonal antibody for imaging prostate cancer
Indium-111 pentetreotide Octreoscan Imaging neuroendocrine tumors
I-123 sodium iodide MallinckrodtAmersham Thyroid imaging and uptake
I-125 iothalamate Glofil Measurement of glomerular filtration
I-125 human serum albumin (RISA) Isojex Plasma volume determinations
I-131sodium iodide Iodotope (Bracco)CIS - I-131Mallinckrodt I-131SolnMallinckrodt I-131 Therapy CapsMallinckrodt I-131 Diagnostic Caps Thyroid uptake, imaging, and therapy
Tositumomab & Iodine I-131 Tositumomab Bexxar Treatment of non-Hodgkin’s lymphoma
I-131 iodomethylnorcholesterol (NP-59) (University of Michigan) Adrenal imaging
I-131 metaiodobenzylguanidine (MIBG) I-131 MIBG Imaging pheochromocytomas and neuroblastomas
P-32 chromic phosphate Phosphocol P32 Therapy for intracavitary malignancies
P-32 sodium phosphate Therapy for polycythemia vera
Rubidium-82 (from Sr-82/Rb-82 generator) Cardio-Gen-82 PET imaging
Samarium-153 Lexidronam (Sm-153 EDTMP) Quadramet Palliative treatment of bone pain of skeletal metastases
Strontium-89 Metastron Palliative treatment of bone pain of skeletal metastases
Tc-99m pertechnetate Generators DuPontMallinckrodt DTEMallinckrodt FMAmersham Imaging thyroid, salivary glands, ectopic gastric mucosa, parathyroid glands, dacryocystography, cystography
Tc-99m Apcitide AcuTect Peptide imaging of deep vein thrombosis
Tc-99m bicisate (ECD) Neurolite Cerebral perfusion imaging
Tc-99m disofenin (DISIDA) Hepatolite-CIS Hepatobiliary imaging
Tc-99m exametazine (HMPAO) Ceretec Cerebral perfusion imaging
Tc-99m Gluceptate DraximageMallinckrodt Renal imaging
Tc-99m human serum albumin (HSA) Imaging cardiac chambers
Tc-99m macroaggregated albumin (MAA) Pulmolite - CISMacrotec (Bracco)Technescan MAA (Mallinckrodt)DraximageAmersham MAA Pulmonary perfusion
Tc-99m Mebrofenin Choletec Hepatobiliary imaging
Tc-99m Medronate (MDP) BraccoOsteolite - CISDraximageMallinckrodtAmersham Bone imaging
Tc-99m Mertiatide Technescan MAG3 Renal imaging
Tc-99m Oxidronate (HDP) Mallinckrodt HDP Bone imaging
Tc-99m Pentetate (DTPA) Techneplex (Bracco)CIS-AN DTPACIS-DTPADraximage DTPAMallinckrodt DTPANycomed DTPARenal imaging and function studies; Radioaerosol ventilation imaging
Tc-99m Pyrophosphate (PYP) Phosphotec (Bracco)Pyrolite-CISPyro-CISTechnescan PYPAmersham PYP Avid infarct imaging; in vivo RBC labeling
Tc-99m red blood cells Ultratag Imaging gastrointestinal (GI) bleeds, cardiac chambers
Tc-99m Sestamibi CardioliteMiralumaMyocardial perfusion imagingBreast tumor imaging
Tc-99m Succimer (DMSA) Amersham DMSA Renal imaging
Tc-99m Sulfur Colloid (SC) CIS-Sulfur ColloidNycomed - SC Imaging liver/spleen, gastric emptying, GI bleeds
Tc-99m Tetrofosmin Myoview Myocardial perfusion imaging
Thallium-201 DuPontMallinckrodtAmersham Myocardial perfusion imaging; Parathyroid and tumor imaging
Y-90 Ibitumomab Tiuxetan Zevalin non-Hodgkin’s lymphoma
Xenon-133 DuPont XenonMallinckrodt XenonAmersham Xenon Pulmonary ventilation imaging
Interventional Agents Trade Name Use in nuclear medicine
ACD solution (anticoagulant acid Acitrate dextrose) ACD Solution Modified Anticoagulant used in blood labeling
Adenosine Adenoscan Pharmacologic stress
Ascorbic acid Ascorbic acid RBC labeling and HDP preparation
I.V. Dipyridamole I.V. Persantine Pharmacologic stress
Sincalide Kinevac Gallbladder ejection fraction studies

SOURCE: University of Arkansas for Medical Sciences (http://nuclearpharmacy.uams.edu/resources/PackageInserts.asp).

Copyright © 2007, National Academy of Sciences.
Bookshelf ID: NBK11481

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