Table 73Harms: trial characteristics

Author, Year
N at Randomization
Population
Setting
Intervention and Comparator
Carter et al., 2009104
N=402
Adults >21 years diagnosed with hypertension

Community-based family medicine residency programs
G1: Physician/pharmacist collaborative model in which pharmacists addressed suboptimal medication regimens and poor medication adherence and gave feedback to physicians. Study nurses gave patients educational information and encouraged lifestyle modifications.
G2: Patients received blood pressure measurements at baseline, 3 and 6 months and educational information from nurses. Clinical pharmacists abstained from providing care to patients in control group.
Murray et al., 2007116
N=314
Adults ≥ 50 years of age with heart failure

University-affiliated ambulatory care practice
G1: Pharmacist-led intervention providing verbal instructions, literacy-sensitive written materials, and labeling of medications with icons to promote medication adherence
G2: No contact with intervention pharmacist other than initial medication history
Schectman et al., 199498
N=102 (Niacin)
N=62 (Bile acid sequestrant)
Adults with hyperlipidemia requiring treatment with either niacin or a bile acid sequestrant

Veterans Affairs medical center
G1: Following initial clinic visit, received five calls over 28 days from a certified medical assistant to address problems and adverse events associated with medications; when needed, additional telephone contact arranged with physician or clinical pharmacist
G2: No telephone contact following initial clinic visit

Abbreviations: G = group; N = number.

From: Results

Cover of Closing the Quality Gap: Revisiting the State of the Science (Vol. 4: Medication Adherence Interventions: Comparative Effectiveness)
Closing the Quality Gap: Revisiting the State of the Science (Vol. 4: Medication Adherence Interventions: Comparative Effectiveness).
Evidence Reports/Technology Assessments, No. 208.4.
Viswanathan M, Golin CE, Jones CD, et al.

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