Table 12Characteristics and results of studies conducting direct and adjusted-indirect comparisons

Author, yearComparisonsPrimary outcomeConclusionQuality
Saad et al., 2010183Adalimumab, etanercept, infliximabQoLAdalimumab, etanercept, and infliximab have similar positive effects on quality of lifeFair
Saad et al., 2008176Adalimumab, etanercept, infliximabACR and PsARCNo statistically significant differences between adalimumab, infliximab, and etanerceptGood
Rodgers et al., 2011177Adalimumab, etanercept, infliximabPsARCNo statistically significant differences between adalimumab, infliximab, and etanercept for probability of achieving PsARC responseGood

Abbreviations: ACR, American College of Rheumatology; PsARC, psoriatic arthritis response criteria; TIM, targeted immune modulator; QoL, quality of life.

From: RESULTS

Cover of Drug Class Review: Targeted Immune Modulators
Drug Class Review: Targeted Immune Modulators: Final Update 3 Report [Internet].
Thaler KJ, Gartlehner G, Kien C, et al.
Portland (OR): Oregon Health & Science University; 2012 Mar.
Copyright © 2012, Oregon Health & Science University, Portland, Oregon.

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