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Thangaratinam S, Rogozińska E, Jolly K, et al. Interventions to Reduce or Prevent Obesity in Pregnant Women: A Systematic Review. Southampton (UK): NIHR Journals Library; 2012 Jul. (Health Technology Assessment, No. 16.31.)

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Interventions to Reduce or Prevent Obesity in Pregnant Women: A Systematic Review.

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Appendix 1List of reviews evaluating the effect of weight management interventions on maternal and fetal outcomes

ReviewQuestionSearch criteriaStudies included
Dodd 2008144Population: overweight and obese women during pregnancy

Intervention: dietary and lifestyle interventions (alone or in combination) to limit weight gain with the intention of improving maternal, fetal and infant health outcomes

Outcomes: weight gain, maternal, fetal and infant health outcomes

Design of included studies: RCTs
Databases searched: MEDLINE, The Cochrane Library, Australian (ACTR) and International (ICTN) Clinical Trials Registry

Hand searching: not stated

Search restrictions: none stated
RCTs: Polley 2002,130 Rae 2000101
Dodd 2010145Population: pregnant women who are overweight or obese

Intervention: antenatal dietary or lifestyle interventions

Outcomes: LGA infants, mean gestational weight gain, hypertension, pre-eclampsia or eclampsia, GDM, preterm birth before 37 weeks of gestation, infection, need for induction of labour, caesarean section, post­partum haemorrhage requiring blood transfusion, perinatal death (stillbirth and neonatal death), congenital anomalies, infant birthweight of > 4500 g, infant birthweight of < 2500 g, Apgar score of <7 at 5 minutes of age, hypoglycaemia requiring intravenous treatment, hyperbilirubinaemia requiring treatment, admission to NICU and birth trauma. Childhood outcomes of relevance relate to body size (including height, weight, and BMI) and body composition

Study design: RCTs
Databases searched: PubMed, CENTRAL, ACTR, ICTN

Hand searching: yes

Search restrictions: no
RCTs: Asbee 2008, Brankston 2004, Guelinckx 2008, Magee 1990, Polley 2002,130 Rae 2000,101 Santos 2005,119 Thornton 2009,102 Wolff 2008103
Kuhlmann 2008146Population: pregnant or post-partum women

Intervention: exercise

Outcomes: pregnancy weight gain in excess of the IOM recommendations or post-partum weight retention

Design of included studies: RCTs
Databases searched: MEDLINE, EMBASE, PsycINFO, Sociological Abstracts, Cumulative Index to Nursing and Allied Health Literature (CINAHL)

Hand searching: yes

Search restrictions: studies published January 1985 to August 2007, English language
RCTs: Leermakers 1998, O'Toole 2003, Polley 2002,130
Leet 2003147Population: pregnant women

Intervention: exercise

Outcomes: infant birthweight

Design of included studies: RCTs, non-randomised controlled studies, observational studies
Databases searched: MEDLINE, Doctor Dissertation Abstracts Online

Hand searching: yes

Search restrictions: English language
Experimental: Bell 2000,132 Carr 1992, Clapp 2000,107 Clapp 2002,108 Collings 1983,52 Erkkola 1976, Lee 1996,115 Marquez-Sterling 2000116

Quasi-experimental: Brenner 1995, Lewis 1998, Webb 1988

Observational: Bell 1995,60 Botkin 1991, Burger 1988, Clapp 1984,62 Clapp 1990, Clapp 1992, Clapp 1995,51 Clapp 1998, Dale 1982,67 Hatch 1993,70 Horns 1996,71 Jackson 1995,72 Johson 1994, Madison 1989, Melgar 1997, Piravej 2001,83 Rice 1991, Sternfeld 1995
Liu 2005148Population: pregnant women

Intervention: an intervention applicable to public health practice consistent with Ontario's Mandatory Health Programs and Services Guidelines; primary prevention and not designed specifically for pregnant women who are obese or diabetic (pregnant or obese women can be included in the study population)

Outcomes: proportion of women exceeding the upper limit of the IOM recommended gestational weight gain range

Design of included studies: RCTs, non-randomised controlled studies, prospective studies with control group
Databases searched: MEDLINE, EMBASE, CINAHL, PsycINFO, Sociological Abstracts, SPORTDiscus

Hand searching: yes

Search restrictions: studies published 1980 to 2005, English language
RCTs: Clapp 1995,51 Olson 2004,81 Polley 2002130
Ronnberg 2010149Population: pregnant women

Exclusion: women with diabetes mellitus

Intervention: intervention studies specifically designed to prevent excessive gestational weight gain

Outcomes: weight gain in pregnancy

Study design: RCTs, NRSs, observational studies
Databases searched: PubMed, The Cochrane Library, CINAHL, Physiotherapy Evidence Database (PEDro)

Hand searching: yes

Search restrictions: limited to English and Scandinavian languages
RCTs: Asbee 2008, Bechtel-Blackwell 2002,93 Polley 2002,130 Wolff 2008103

NRSs and observational: Claesson 2008,49 Gray-Donald 2000,54 Kinnunen 2007,57 Olson 200481
Scharr 201022Population: pregnant women expecting a single baby, women seeking preconception advice, women actively planning a pregnancy

Intervention: dietary and/or physical activity advice, personal one-to-one and group counselling, physical activity groups or classes, educational and informative literature given to pregnant women, monitoring by health professionals or self-assessment, tracking of progress and tailoring programmes to meet current needs of pregnant women

Outcomes: weight-related outcomes, dietary and physical activity outcomes, other mother-related outcomes, outcomes relating to the infant

Design of included studies: RCTs, NRSs, observational studies
Databases searched: MEDLINE, EMBASE, The Cochrane Library, Science Citation Index, ClinicalTrials.com, UK Clinical Research Network Portfolio, other: Applied Social Sciences Index and Abstracts (ASSIA) via CSA, British Nursing Index via OVID SP, CINAHL via OVID SP, EconLit via OVID SP, Maternity and Infant Care via OVID SP, PyscINFO via OVID SP, Social Science Citation Index via Web of Science

Hand searching: yes

Search restrictions: searches were limited by year (1990–2008) and to human studies (where this option was available)
RCTs: Asbee 2008, Guelinckx 2008, Hui 2002, Polley 2002,130 Wolff 2008103

NRSs: Claesson 2008,49 Gray-Donald 2000,54 Kardel 1998,56 Kinnunen 2007,57 Olson 200481

Case series: Galletly 1996, Mendelson 1991

Observational: Bergmann 1997, Bungum 1999, Cambell 2001, Cogswell 1996, Conway 1999,66 Gunderson 2004, Horns 1996,71 Keppel 1993, Lof 2008, Mumford 2008, Olson 2003, Sternfeld 1995, Symons Downs 2007, Taffel 1993
Schlüssel 2008150Population: pregnant women

Intervention: physical activity for pregnant women: (1) occupational physical activities and (2) leisure-time physical activities

Outcomes: pre-eclampsia, gestational arterial hypertension, GDM, gestational weight gain, miscarriage, mode of delivery, fetal growth or development, birthweight, length at birth or prematurity

Design of included studies: cross-sectional, case–control or follow-up (cohort) epidemiological studies
Databases searched: MEDLINE, LILACS

Hand searching: yes

Search restrictions: published between 1980 and 2005, Portuguese, English, or Spanish language
Cohort: Begun 2000, Bell 1995, Clapp 1989, Clapp and Little 1995, Dempsey 2004, Florack 1993, Florack 1995, Hatch 1993, Hatch 1998, Henriksen 1995, Horns 1996, Jarrett and Sppelday 1983, Klebanoff 1990, Koemeester 1995, Magann 2002, Misra 1998, Rabkin 1990, Rao 2003, Rose 1991, Saftlas 2004, Stamfeld 1995, Takito 2005

Case–control: Alderman 1998, Berkowitz 1983, Campbell and Mottola 2001, Carmichael 2002, Dempsey 2004, El Metwall 2001, Letke 1999, Marcoux 1989, Schramm 1996, Sorensen 2003, Spinillo 1995, Spinillo 1996

Cross-sectional: Dye 1997, Leiferman and Evenson 2003
Skouteris 2010151Population: pregnant women

Intervention: intervention studies specifically designed to prevent excessive gestational weight gain; interventions specifically targeting diabetes mellitus and/or designed for adolescents or post-partum women were excluded

Outcomes: excessive weight gain in pregnancy

Study design: RCTs, NRSs, observational studies
Databases searched: CINAHL, Global Health, MEDLINE, PsycINFO, Academic Search Premier

Hand searching: not stated

Search restrictions: limited to English papers published between January 2000 and April 2010
RCTs: Asbee 2008, Guelinckx 2008, Hui 2002, Jeffries 2009,128 Polley 2002,130 Wolff 2008103

NRSs: Claesson 2008,49 Gray-Donald 2000,54 Kinnunen 2007,57 Olson 200481
© 2012, Crown Copyright.

Included under terms of UK Non-commercial Government License.

Bookshelf ID: NBK109445

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