nuclear factor of activated T cells

The transcription factor called nuclear factor of activated T cells (NFAT) is a complex of a protein called NFATc, as it is held in the cytosol by serine/threonine phosphorylation, and the Fos/Jun dimer known as AP-1. It moves from the cytosol to the nucleus on cleavage of the phosphate residues by calcineurin, a serine/threonine protein phosphatase.