Forest plot 11 is a metagraph comparing the adverse events between patients receiving haloperidol versus risperidone. Eight studies (n=1,313) were pooled together and found that adverse events occurred significantly less with risperidone (MD=1.20, 95 percent CI, 1.01, 1.42); however statistical heterogeneity was considerable (p<0.00001, I2=84%).

Forest plot 11Haloperidol versus risperidone–Incidence of patients with adverse events

CI = confidence intervals; df = degrees of freedom; I2 = I–squared; IV = inverse variance; M-H = Mantel-Haenszel

From: Appendix J, Forest Plots for Adverse Events

Cover of First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness
First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness [Internet].
Comparative Effectiveness Reviews, No. 63.
Abou-Setta AM, Mousavi SS, Spooner C, et al.

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