Table 51Characteristics of RCTs comparing perphenazine versus olanzapine in the treatment of schizophrenia

Study, Design (Followup)Interventions, Dosages; No. RandomizedMain Inclusion CriteriaRisk of Bias,
Financial Support
Ascher-Svanum et al. 2008131
RCT (1 yr)
G1: PER (NR); (48)
G2: OLA (NR); (229)
Sz, schizoaffective or schizophreniform disorders; BPRS ≥18Unclear,
Industry
Lieberman et al. 200523
RCT (18 mo)
G1: PER (8–32mg/d); (261)
G2: OLA (7.5–30mg/d); (336)
Sz defined by DSM–IVUnclear,
Multiple sources including industry

BPRS = Brief Psychiatric Rating Scale; D = day; DSM–IV = Diagnostic and Statistical Manual, 4th edition; G = group; Mg = milligrams; Mo = month(s); No. = number; NR = not reported; OLA = olanzapine; PER = perphenazine; RCT = randomized controlled trial; Sz = schizophrenia; Yr(s) = year(s)

From: Results

Cover of First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness
First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness [Internet].
Comparative Effectiveness Reviews, No. 63.
Abou-Setta AM, Mousavi SS, Spooner C, et al.

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