Table 32Strength of evidence (GRADE): haloperidol versus asenapine

OutcomeSourceRoBConsistencyDirectnessPrecisionSoE
Positive Symptoms
PANSS1 RCTMediumUnknownDirectImpreciseInsufficient
Negative Symptoms
PANSS1 RCTMediumUnknownDirectImpreciseInsufficient
General Psychopathology
CDS–S1 RCTMediumUnknownDirectImpreciseInsufficient
PANSS1 RCTMediumUnknownDirectImpreciseInsufficient
Global Ratings and Total Scores
CGI–S1 RCTMediumUnknownDirectImpreciseInsufficient
PANSS1 RCTMediumUnknownDirectImpreciseInsufficient

CDS–S = Calgary Depression Scale for Schizophrenia; CGI–S = Clinical Global Impression–Severity; PANSS = Positive and Negative Symptom Scale; RCT = randomized controlled trial; RoB = risk of bias; SoE = Strength of Evidence

From: Results

Cover of First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness
First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness [Internet].
Comparative Effectiveness Reviews, No. 63.
Abou-Setta AM, Mousavi SS, Spooner C, et al.

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